KIN antibody (N-Term)

Catalog No. ABIN3031547

Product Details anti-KIN Antibody

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIN antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human KIN (ESHQRQLLLASENPQQF) was used as the immunogen for this KIN17 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the KIN17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the KIN17 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for KIN

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Alternative Name: KIN17 (KIN Products)

Synonyms: Kin17 antibody, BTCD antibody, KIN17 antibody, Kin17 DNA and RNA binding protein antibody, Kin17 DNA and RNA binding protein S homeolog antibody, Kin antibody, kin.S antibody, KIN antibody

Background: DNA/RNA-binding protein KIN17, also known as BTCD, is a protein that in humans is encoded by the KIN gene. This gene is mapped to 10p14. The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.

UniProt: O60870