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LRRK2 antibody (Leucine-Rich Repeat Kinase 2) (C-Term) Primary Antibody

LRRK2 Reactivity: Human, Mouse ELISA, WB Host: Mouse Monoclonal 133AT720 unconjugated
Catalog No. ABIN3031611
$521.13
Plus shipping costs $45.00
0.4 mL ABIN3031611
0.4 mL ABIN3031611
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  • Target
    LRRK2
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 1
    C-Term
    Reactivity
    Human, Mouse
    Host
    • 8
    • 2
    Mouse
    Clonality
    • 8
    • 2
    Monoclonal
    Application
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB)
    Purification
    Purified
    Immunogen
    This LRRK2 antibody was raised in mice using purified His-tagged recombinant protein comprised of the C-terminal 261 residues of LRRK2.
    Clone
    133AT720
    Isotype
    IgG1
  • Application Notes
    Titration of the LRRK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the LRRK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    LRRK2
    Alternative Name
    LRRK2 (LRRK2 Antibody Abstract)
    Synonyms
    LRRK2, AURA17, DARDARIN, PARK8, RIPK7, ROCO2, 4921513O20Rik, 9330188B09Rik, AW561911, D630001M17Rik, Gm927, cI-46, leucine-rich repeat kinase 2, leucine rich repeat kinase 2, lrrk2, LRRK2, Lrrk2
    Background
    This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
    UniProt
    Q5S007
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
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