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Myelin Basic Protein (MBP) antibody Primary Antibody

MBP Reactivity: Human IF, ELISA, WB Host: Mouse Monoclonal 408CT17-4-3 unconjugated
Catalog No. ABIN3031733
$507.38
Plus shipping costs $45.00
0.1 mL
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  • Target
    Myelin Basic Protein (MBP)
    Reactivity
    • 139
    • 47
    • 37
    • 35
    • 17
    • 16
    • 12
    • 12
    • 9
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 91
    • 48
    • 13
    • 10
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 101
    • 63
    Monoclonal
    Conjugate
    • 118
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 98
    • 71
    • 51
    • 23
    • 22
    • 19
    • 15
    • 15
    • 12
    • 10
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (IF), ELISA, Western Blotting (WB)
    Purification
    Ascites
    Immunogen
    Purified His-tagged protein fragment was used to produced this monoclonal anti-MBP antibody.
    Clone
    408CT17-4-3
    Isotype
    IgM
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the anti-MBP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:5000-1:16000,Immunofluorescence: 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In ascites with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the anti-MBP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Myelin Basic Protein (MBP)
    Alternative Name
    Myelin basic protein (MBP Antibody Abstract)
    Synonyms
    C76307, Hmbpr, R75289, golli-mbp, mld, shi, Mbps, cb274, fj33b11, mbp, wu:fj33b11, wu:fq15b02, zgc:136630, MGC115135, MBP, mMBP, mMBP-1, myelin basic protein, myelin basic protein a, myelin basic protein L homeolog, proteoglycan 2, bone marrow, MBP, Mbp, mbpa, mbp, mbp.L, Prg2
    Background
    The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq].
    UniProt
    P02686
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