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Parkin antibody (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin)) (AA 111-140) Primary Antibody

PARK2 Reactivity: Human FACS, IF, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032153
$493.63
Plus shipping costs $45.00
0.4 mL ABIN3032153
0.4 mL ABIN3032153
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  • Target
    Parkin (PARK2)
    Binding Specificity
    • 18
    • 17
    • 13
    • 11
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-140
    Reactivity
    • 114
    • 45
    • 37
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 124
    • 9
    • 5
    Rabbit
    Clonality
    • 129
    • 8
    Polyclonal
    Conjugate
    • 82
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Parkin antibody is un-conjugated
    Application
    • 87
    • 55
    • 41
    • 39
    • 29
    • 21
    • 21
    • 13
    • 9
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 111-140 from the human protein was used as the immunogen for this Parkin antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the Parkin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:250-1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the Parkin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Parkin (PARK2)
    Alternative Name
    Parkin (PARK2 Antibody Abstract)
    Synonyms
    CG10523, Dmel\\CG10523, Dpark, SD01679, dpk, AR-JP, LPRS2, PDJ, PRKN, Park, Prkn, si:ch211-123f21.1, zgc:112390, pdr-1, PARK2, parkin, parkin RBR E3 ubiquitin protein ligase, Parkinson disease (autosomal recessive, juvenile) 2, parkin, park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
    Background
    Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known, however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function.
    UniProt
    O60260
    Pathways
    Autophagy, Ubiquitin Proteasome Pathway
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