PPIB antibody (C-Term)

Catalog No. ABIN3032177

Product Details anti-PPIB Antibody

Target: PPIB (Cyclophilin B (PPIB))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human CYPB (MEVVRKVESTKTDSRDKPLKD) was used as the immunogen for this Cyclophilin B antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Cyclophilin B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Cyclophilin B antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for PPIB

Target: PPIB (Cyclophilin B (PPIB))

Alternative Name: Cyclophilin B (PPIB Products)

Synonyms: cypb antibody, scylp antibody, cyp-s1 antibody, PPIB antibody, Ppib antibody, ACYPI004891 antibody, AA408962 antibody, AA553318 antibody, AI844835 antibody, Cphn-2 antibody, Cphn2 antibody, CyP-20b antibody, CypB antibody, Scylp antibody, CYP-S1 antibody, CYPB antibody, OI9 antibody, SCYLP antibody, cb87 antibody, sb:cb87 antibody, wu:fa97f08 antibody, zgc:73214 antibody, zgc:86796 antibody, peptidylprolyl isomerase B antibody, peptidylprolyl isomerase B (cyclophilin B) antibody, peptidylprolyl isomerase B L homeolog antibody, ppib antibody, PPIB antibody, Ppib antibody, CC1G_03223 antibody, ppib.L antibody

Background: Cyclophilin B, also known as CYPB, is an enzyme that in humans is encoded by the PPIB gene. This gene is mapped to 15q22.31. The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. Cyclophilin B can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

UniProt: P23284