PFN1 antibody (C-Term)

Catalog No. ABIN3032304

Product Details anti-PFN1 Antibody

Target: PFN1 (Profilin 1 (PFN1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFN1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human PFN1 (KEGVHGGLINKKCYEMASHLRRSQY) was used as the immunogen for this Profilin-1 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Profilin-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Profilin-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for PFN1

Target: PFN1 (Profilin 1 (PFN1))

Alternative Name: Profilin-1 (PFN1 Products)

Synonyms: GmPRO1 antibody, GmPRO2 antibody, PRO1 antibody, Profilin-1 antibody, profilin-1 antibody, profilin antibody, MGC130883 antibody, Profilin1 antibody, XProfilin1 antibody, sb:cb813 antibody, wu:fa91a03 antibody, ALS18 antibody, Pfn antibody, F6F22.21 antibody, F6F22_21 antibody, PFN1 antibody, PROFILIN 1 antibody, profilin 1 antibody, profilin antibody, profilin 1 antibody, profilin 1 L homeolog antibody, profilin homolog 1 antibody, Profilin-1 antibody, PRO2 antibody, PFN1 antibody, pfn1.L antibody, pfn1 antibody, Pfn1 antibody, PRF1 antibody, prf1 antibody, pfn-1 antibody

Background: Profilin-1 is a protein that in humans is encoded by the PFN1 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. At high concentrations, Profilin-1 prevents the polymerization of actin, whereas it enhances it at low concentrations. This gene is a 140-amino acid protein and major growth regulator of filamentous (F)-actin through its binding of monomeric (G)-actin. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.

Gene ID: 5216

Pathways: Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location