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PFN2 antibody (C-Term)

PFN2 Reactivity: Human, Mouse, Rat IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032305
$635.25
Plus shipping costs $45.00
100 μg
Shipping to: United States
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  • Target See all PFN2 Antibodies
    PFN2 (Profilin 2 (PFN2))
    Binding Specificity
    • 15
    • 11
    • 10
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 58
    • 15
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 55
    • 3
    Rabbit
    Clonality
    • 55
    • 3
    Polyclonal
    Conjugate
    • 22
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PFN2 antibody is un-conjugated
    Application
    • 39
    • 23
    • 13
    • 13
    • 9
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human PFN2 (NKKAYSMAKYLRDSGF) was used as the immunogen for this Profilin 2 antibody (100% homologous in human, mouse and rat).
    Isotype
    IgG
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the Profilin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the Profilin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PFN2 (Profilin 2 (PFN2))
    Alternative Name
    Profilin 2 (PFN2 Products)
    Synonyms
    D3S1319E antibody, PFL antibody, Pfn antibody, Profilin2 antibody, XProfilin2 antibody, PFN2 antibody, PRO2 antibody, Profilin-2 antibody, pfl antibody, d3s1319e antibody, profilin-2 antibody, F17A13.170 antibody, F17A13_170 antibody, PRF2 antibody, PROFILIN antibody, PROFILIN 2 antibody, profilin 2 antibody, wu:fb01g08 antibody, wu:fb54f09 antibody, wu:fd58f06 antibody, profilin 2 antibody, profilin 2 L homeolog antibody, profilin homolog 2 antibody, Profilin-2 antibody, PFN2 antibody, Pfn2 antibody, pfn2.L antibody, prf2 antibody, pfn2 antibody, pfn-2 antibody
    Background
    Profilin-2 is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Profilin-2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, it prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
    UniProt
    P35080
    Pathways
    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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