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PINK1 antibody

PINK1 Reactivity: Human, Mouse IHC, ELISA, WB Host: Mouse Monoclonal 38CT20-8-5 unconjugated
Catalog No. ABIN3032404
$592.75
Plus shipping costs $45.00
0.1 mL
Shipping to: United States
Delivery in 2 to 3 Business Days
  • Target See all PINK1 Antibodies
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    Reactivity
    • 95
    • 54
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 74
    • 37
    • 7
    Mouse
    Clonality
    • 84
    • 36
    Monoclonal
    Conjugate
    • 50
    • 11
    • 10
    • 8
    • 8
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This PINK1 antibody is un-conjugated
    Application
    • 94
    • 66
    • 46
    • 18
    • 16
    • 7
    • 5
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Purification
    Ascites
    Immunogen
    Recombinant protein was used to produced this PINK1 antibody.
    Clone
    38CT20-8-5
    Isotype
    IgG1
  • Application Notes
    Titration of the PINK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500-1:2000,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In ascites with 0.09 % sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the PINK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
    Alternative Name
    PINK1 (PINK1 Products)
    Synonyms
    BEST:GH23468 antibody, CG4523 antibody, Dmel\\CG4523 antibody, PINK antibody, PINK1 antibody, dPINK1 antibody, dPink1 antibody, pink1 antibody, wu:fc39e12 antibody, zgc:101729 antibody, BRPK antibody, PARK6 antibody, 1190006F07Rik antibody, AU042772 antibody, AW557854 antibody, mFLJ00387 antibody, PTEN-induced putative kinase 1 antibody, PTEN induced putative kinase 1 antibody, Pink1 antibody, PINK1 antibody, pink1 antibody
    Background
    PINK1 protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form. [UniProt]
    UniProt
    Q9BXM7
    Pathways
    Autophagy
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