SERPINH1 antibody (AA 247-418)

Catalog No. ABIN3032548

Product Details anti-SERPINH1 Antibody

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Binding Specificity: AA 247-418

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 247-418) was used as the immunogen for this HSP47 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the HSP47 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the HSP47 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for SERPINH1

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Alternative Name: HSP47 (SERPINH1 Products)

Synonyms: AsTP3 antibody, CBP1 antibody, CBP2 antibody, HSP47 antibody, OI10 antibody, PPROM antibody, RA-A47 antibody, SERPINH2 antibody, gp46 antibody, SERPINH1 antibody, DKFZp468B197 antibody, cb216 antibody, hsp antibody, hsp47 antibody, id:ibd5060 antibody, wu:fc56b02 antibody, BERF-1 antibody, Cbp1 antibody, Cbp2 antibody, Hsp47 antibody, J6 antibody, Serpinh2 antibody, colligin antibody, astp3 antibody, cbp1 antibody, cbp2 antibody, pig14 antibody, pprom antibody, ra-a47 antibody, serpinh2 antibody, serpin family H member 1 antibody, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b antibody, serpin H1 antibody, selenoprotein K antibody, serine (or cysteine) peptidase inhibitor, clade H, member 1 antibody, serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) L homeolog antibody, SERPINH1 antibody, serpinh1b antibody, LOC100009353 antibody, Selenok antibody, Serpinh1 antibody, serpinh1.L antibody

Target Type: Viral Protein

Background: Heat shock protein 47, also known as SERPINH1, is a serpin which serves as a human chaperone protein for collagen. It is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. HSP47 localizes to the endoplasmic reticulum lumen and binds collagen, thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. It has been found that HSP47 monitors the integrity of the triple helix of type I procollagen at the ER/cis-Golgi boundary and, when absent, the rate of transit from the ER to the Golgi is increased and the helical structure is compromised.

Gene ID: 871