SIRT3 antibody (AA 66-399)

Catalog No. ABIN3032592

Product Details anti-SIRT3 Antibody

Target: SIRT3 (Sirtuin 3 (SIRT3))

Binding Specificity: AA 66-399

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 66-399) was used as the immunogen for this SIRT3 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the SIRT3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Alternative Name: SIRT3 (SIRT3 Products)

Synonyms: zgc:158774 antibody, sirtuin antibody, SIR2L3 antibody, 2310003L23Rik antibody, AI848213 antibody, Sir2l3 antibody, sirtuin 3 antibody, sirt3 antibody, SIRT3 antibody, Sirt3 antibody

Background: NAD-dependent deacetylase sirtuin-3, mitochondrial is a protein that in humans is encoded by the SIRT3 gene. It is member of the mammalian sirtuin family of proteins, which are homologs to the yeast Sir2 protein. Endogenous SIRT3 is a soluble protein located in the mitochondrial matrix. Overexpression in cultured cells increases respiration and decreases the production of reactive oxygen species. It can function as a mitochondrial deacetylase. Additionally, human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.

Gene ID: 23410