Lamin A/C antibody (LMNA) (AA 464-572)

Details for Product anti-LMNA Antibody No. ABIN303591, Supplier: Log in to see
Antigen
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • Dhe
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • lmna-A
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • lamin-L(III)-like
  • lamin A/C
  • lamin A
  • Lamin
  • lamin A/C L homeolog
  • lamin-L(III)-like
  • LMNA
  • Lmna
  • Lam
  • lmna
  • lmna.L
  • LMINA
Alternatives
anti-Mouse (Murine) Lamin A/C antibody for Western Blotting
Epitope
AA 464-572
35
27
24
21
20
18
17
11
11
10
9
9
7
7
7
6
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Green monkey (Chlorocebus), Human
445
272
236
104
54
51
24
21
15
10
8
7
5
4
3
3
2
2
1
1
1
Host
Mouse
232
220
5
1
Clonality (Clone)
Monoclonal ()
Conjugate
This Lamin A/C antibody is un-conjugated
13
12
10
7
7
7
7
6
6
6
6
6
6
6
5
5
4
4
4
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
408
210
199
163
118
113
77
73
55
17
14
11
2
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Recombinant human lamin A
Clone JOL2
Isotype IgG1
Specificity This antibody reacts with both recombinant and native Lamin A and C in humans. Binds to an epitope between amino acids 464-572
Purification Unpurified
Plasmids, Primers & others Plasmids, Primers & others Lamin A/C products on genomics-online (e.g. as negative or positive controls)
Alternative Name Lamin A+C (LMNA Antibody Abstract)
Background Synonyms:
70 kDa Lamin antibody,Cardiomyopathy dilated 1A (autosomal dominant) antibody,CDCD1 antibody,CDDCantibody,Charcot Marie Tooth Disease Axonal Type 2B1 antibody,CMD1A antibody,CMT2B1 antibody,EMD2antibody,FPL antibody,FPLD antibody,HGPS antibody,IDC antibody,Lamin A/C antibody,Lamin A/C Isoform 1Precursor antibody,Lamin A/C Isoform 2 antibody,Lamin A/C Isoform 3 antibody,LDP1 antibody,LFPantibody,LGMD1B antibody,Limb girdle muscular dystrophy 1B (autosomal dominant) antibody,LMN 1 antibody,LMN Aantibody,LMN C antibody,LMN1 antibody,LMNA antibody,LMNC antibody,NY REN 32 antigen antibody,PRO1antibody,Progeria 1 (Hutchinson Gilford Type) antibody,Renal carcinoma antigen NY REN 32 antibody,Renalcarcinoma antigen NYREN32 antibody
Gene ID 4000
OMIM 150330
UniProt P02545
Pathways Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
Application Notes Optimal antibody dilution should be determined by titration, however as a guideline try, WB: 1/200. Predicted molecular weight: 74 kDa Flow Cyt: 1/10 IP: Use neat
Restrictions For Research Use only
Format Liquid
Buffer Tissue culture supernatant containing 0.2M Tris/HCl pH 7.4 and 510 % foetal calf serum,
Storage 4 °C
Supplier Images
Immunofluorescence (IF) image for anti-Lamin A/C (LMNA) (AA 464-572) antibody (ABIN303591) Immunofluorescence staining of Lamin A/C (clone JOL2) and Ki67 on Human dermal fibrob...
Immunohistochemistry (IHC) image for anti-Lamin A/C (LMNA) (AA 464-572) antibody (ABIN303591) anti-Lamin A/C (LMNA) (AA 464-572) antibody (Image 2)
Product cited in: Iglesias-Guimarais, Gil-Guiñon, Gabernet, García-Belinchón, Sánchez-Osuna, Casanelles, Comella, Yuste: "Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease." in: The Journal of biological chemistry, Vol. 287, Issue 10, pp. 7766-79, 2012 (PubMed).

Gudise, Figueroa, Lindberg, Larsson, Hallberg: "Samp1 is functionally associated with the LINC complex and A-type lamina networks." in: Journal of cell science, Vol. 124, Issue Pt 12, pp. 2077-85, 2011 (PubMed).

Harrigan, Belotserkovskaya, Coates, Dimitrova, Polo, Bradshaw, Fraser, Jackson: "Replication stress induces 53BP1-containing OPT domains in G1 cells." in: The Journal of cell biology, Vol. 193, Issue 1, pp. 97-108, 2011 (PubMed).

Harten, Zahr, Lemire, Machan, Moses, Doiron, Curatolo, Rothman, Wight, Toole, Gordon: "Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome." in: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 66, Issue 11, pp. 1201-7, 2011 (PubMed).

Mamchaoui, Trollet, Bigot, Negroni, Chaouch, Wolff, Kandalla, Marie, Di Santo, St Guily, Muntoni, Kim, Philippi, Spuler, Levy, Blumen, Voit, Wright, Aamiri, Butler-Browne, Mouly: "Immortalized pathological human myoblasts: towards a universal tool for the study of neuromuscular disorders." in: Skeletal muscle, Vol. 1, pp. 34, 2011 (PubMed).

Toulany, Schickfluss, Eicheler, Kehlbach, Schittek, Rodemann: "Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation." in: Breast cancer research : BCR, Vol. 13, Issue 2, pp. R28, 2011 (PubMed).

Negroni, Riederer, Chaouch, Belicchi, Razini, Di Santo, Torrente, Butler-Browne, Mouly: "In vivo myogenic potential of human CD133+ muscle-derived stem cells: a quantitative study." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 17, Issue 10, pp. 1771-8, 2009 (PubMed).

Vaughan, Alvarez-Reyes, Bridger, Broers, Ramaekers, Wehnert, Morris, Whitfield WGF, Hutchison: "Both emerin and lamin C depend on lamin A for localization at the nuclear envelope." in: Journal of cell science, Vol. 114, Issue Pt 14, pp. 2577-90, 2001 (PubMed).

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