DREAM antibody (N-Term)

Catalog No. ABIN3042562

Product Details anti-DREAM Antibody

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Binding Specificity: AA 1-16, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DREAM antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Calsenilin(KCNIP3) detection. Tested with WB in Human.

Sequence: MQPAKEVTKA SDGSLL

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Calsenilin(KCNIP3) detection. Tested with WB in Human.
Gene Name: Kv channel interacting protein 3, calsenilin
Protein Name: Calsenilin

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CSEN(1-16aa MQPAKEVTKASDGSLL).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for DREAM

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Alternative Name: KCNIP3 (KCNIP3 Products)

Synonyms: CSEN antibody, DREAM antibody, KCHIP3 antibody, 4933407H12Rik antibody, AI413860 antibody, Csen antibody, KChIP3 antibody, R74849 antibody, Dream antibody, rKChIP3 antibody, csen antibody, im:7145308 antibody, kcnip3 antibody, zgc:73306 antibody, KCNIP3 antibody, potassium voltage-gated channel interacting protein 3 antibody, Kv channel-interacting protein 4 antibody, calsenilin antibody, Kv channel interacting protein 3, calsenilin antibody, Kv channel interacting protein 3b, calsenilin antibody, KCNIP3 antibody, LOC5568664 antibody, CpipJ_CPIJ002549 antibody, Tsp_05009 antibody, Kcnip3 antibody, kcnip3b antibody, kcnip3 antibody

Background: KCNIP3, also known as Calsenilin, is a calcium-dependent transcriptional repressor that is highly expressed in central nervous system, thyroid gland, testis, thymus, and immune cells. This gene encodes a member of the family of voltage-gated potassium(Kv) channel-interacting proteins, which belong to the neuronal calcium sensor family of proteins. KCNIP3 is mapped to 2q11.1. The encoded protein functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. KCNIP3-regulated genes have a critical function in Ig subclass production and proliferation in B lymphocytes. KCNIP3 has been shown to interact with PSEN1 and PSEN2.

Synonyms: 4933407H12Rik antibody|A type potassium channel modulatory protein 3 antibody|A-type potassium channel modulatory protein 3 antibody|AI413860 antibody|Calsenilin antibody|CSEN antibody||DRE Antagonist Modulator antibody|DRE-antagonist modulator antibody|DREAM antibody|EF Hand Transcription Factor antibody|KCHIP 3 antibody|KCHIP3 antibody|KCNIP 3 antibody|KCNIP3 antibody|Kv channel interacting protein 3 antibody|Kv channel-interacting protein 3 antibody|MGC18289 antibody|Potassium channel interacting protein 3 antibody|Presenilin Binding Protein antibody|R74849 antibody

UniProt: Q9Y2W7