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IRF1 antibody (Middle Region)

IRF1 Reactivity: Human WB, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042646
  • Target See all IRF1 Antibodies
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Binding Specificity
    • 10
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 169-183, Middle Region
    Reactivity
    • 87
    • 48
    • 34
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Human
    Host
    • 91
    • 6
    • 1
    • 1
    Rabbit
    Clonality
    • 83
    • 16
    Polyclonal
    Conjugate
    • 48
    • 12
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRF1 antibody is un-conjugated
    Application
    • 87
    • 33
    • 14
    • 12
    • 11
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Interferon regulatory factor 1(IRF1) detection. Tested with WB, IHC-P, ICC in Human.
    Sequence
    YMQDLEVEQA LTPAL
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Interferon regulatory factor 1(IRF1) detection. Tested with WB, IHC-P, ICC in Human.
    Gene Name: interferon regulatory factor 1
    Protein Name: Interferon regulatory factor 1
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human IRF1(169-183aa YMQDLEVEQALTPAL).
    Isotype
    IgG
    Top Product
    Discover our top product IRF1 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
  • Target
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Alternative Name
    IRF1 (IRF1 Products)
    Synonyms
    irf1 antibody, zgc:136945 antibody, IRF1 antibody, irf11 antibody, zgc:103566 antibody, IRF-1 antibody, MAR antibody, AU020929 antibody, Irf-1 antibody, interferon regulatory factor 1 antibody, interferon regulatory factor 1a antibody, interferon regulatory factor 1b antibody, IRF1 antibody, irf1a antibody, irf1b antibody, Irf1 antibody
    Background
    Interferon regulatory factor 1, also known as MAR is a protein that in humans is encoded by the IRF1 gene. The IRF1 gene is mapped to chromosome 5q31.1 by pulsed-field gel electrophoresis. IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor(IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

    Synonyms: MAR antibody|IRF-1 antibody|interferon regulatory factor-1 antibody
    UniProt
    P10914
    Pathways
    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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