IKBKG antibody (N-Term)

Catalog No. ABIN3042676

Product Details anti-IKBKG Antibody

Target: IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))

Binding Specificity: AA 1-15, N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKBKG antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for NF-kappa-B essential modulator(IKBKG) detection. Tested with WB in Mouse.

Sequence: MNKHPWKNQL SEMVQ

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for NF-kappa-B essential modulator(IKBKG) detection. Tested with WB in Mouse.
Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Protein Name: NF-kappa-B essential modulator(NEMO)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse IKK gamma(1-15aa MNKHPWKNQLSEMVQ), different from the relative rat sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for IKBKG

Target: IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))

Alternative Name: IKBKG (IKBKG Products)

Synonyms: AMCBX1 antibody, FIP-3 antibody, FIP3 antibody, Fip3p antibody, IKK-gamma antibody, IP antibody, IP1 antibody, IP2 antibody, IPD2 antibody, NEMO antibody, ZC2HC9 antibody, 1110037D23Rik antibody, AI848108 antibody, AI851264 antibody, AW124339 antibody, IKK[g] antibody, Nemo antibody, nemo antibody, fj33c07 antibody, wu:fj33c07 antibody, zgc:113492 antibody, MGC97885 antibody, IKBKG antibody, IKBKG_1 antibody, IKBKG_2 antibody, CG16910 antibody, DmIKK-gamma antibody, DmIKKgamma antibody, Dmel\\CG16910 antibody, Dmikkgamma antibody, IKK antibody, IKK[[gamma]] antibody, IKKg antibody, IKKgamma antibody, KEY antibody, Kenny antibody, Key antibody, dIKK antibody, dIKK-gamma antibody, dmIKKgamma antibody, inhibitor of nuclear factor kappa B kinase subunit gamma antibody, inhibitor of kappaB kinase gamma antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma antibody, inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog antibody, kenny antibody, IKBKG antibody, Ikbkg antibody, ikbkg antibody, ikbkg.L antibody, IKBKG_1 antibody, key antibody

Background: NF-kappa-B essential modulator (NEMO), also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ), is a protein that in humans is encoded by the IKBKG gene. This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Synonyms: IkB kinase associated protein 1 antibody|IkB kinase subunit gamma antibody|Inhibitor of nuclear factor kappa B kinase subunit gamma antibody|AMCBX1 antibody|FIP 3 antibody|FIP-3 antibody|FIP3 antibody|Fip3p antibody|I kappa B kinase gamma antibody|I-kappa-B kinase subunit gamma antibody|IkB kinase associated protein 1 antibody|IkB kinase gamma subunit antibody|IkB kinase subunit gamma antibody|IkB kinase-associated protein 1 antibody|IKBKG antibody|IKK-gamma antibody|IKKAP 1 antibody|IKKAP1 antibody|IKKG antibody|Incontinentia pigmenti antibody|Inhibitor of kappa light polypeptide gene enhancer in B cells kinase gamma antibody|Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma antibody|Inhibitor of nuclear factor kappa B kinase gamma subunit antibody|Inhibitor of nuclear factor kappa B kinase subunit gamma antibody|Inhibitor of nuclear factor kappa-B kinase subunit gamma antibody|IP 1 antibody|IP 2 antibody|IP antibody|IP1 antibody|IP2 antibody|IPD2 antibody|NEMO antibody|NEMO_HUMAN antibody|NF kappa B essential modifier antibody|NF kappa B essential modulator antibody|NF kappaB essential modifier antibody|NF kappaB essential modulator antibody|NF-kappa-B essential modifier antibody|NF-kappa-B essential modulator antibody|NFkappaB essential modulator antibody|ZC2HC9 antibody

UniProt: O88522

Pathways: NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, M Phase, Production of Molecular Mediator of Immune Response, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins