SERPINA6 antibody (N-Term)

Catalog No. ABIN3042818

Product Details anti-SERPINA6 Antibody

Target: SERPINA6 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6))

Binding Specificity: AA 102-120, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Corticosteroid-binding globulin(SERPINA6) detection. Tested with WB, IHC-P, ICC in Human.

Sequence: ETEIHQGFQH LHQLFAKSD

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Corticosteroid-binding globulin(SERPINA6) detection. Tested with WB, IHC-P, ICC in Human.
Gene Name: serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 6
Protein Name: Corticosteroid-binding globulin

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Cortisol Binding Globulin(102-120aa ETEIHQGFQHLHQLFAKSD).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SERPINA6

Target: SERPINA6 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6))

Alternative Name: SERPINA6 (SERPINA6 Products)

Synonyms: ep45-A antibody, SERPINA6 antibody, AI265318 antibody, AV104445 antibody, Cbg antibody, CBG antibody, serpin family A member 6 antibody, serpin family A member 6 L homeolog antibody, corticosteroid-binding globulin antibody, serine (or cysteine) peptidase inhibitor, clade A, member 6 antibody, SERPINA6 antibody, serpina6.L antibody, LOC490838 antibody, Serpina6 antibody

Background: Corticosteroid-binding globulin(CBG), also known as Serpin A6 is a protein that in humans is encoded by the SERPINA6 gene. It is mapped 14q32.13. This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.

Synonyms: CBG antibody|CBG_HUMAN antibody|corticosteroid binding globulin antibody|Corticosteroid-binding globulin antibody|serine(or cysteine) proteinase inhibitor clade A(alpha 1 antiproteinase antitrypsin) member 6 antibody|Serpin A6 antibody|serpin peptidase inhibitor clade A(alpha 1 antiproteinase antitrypsin) member 6 antibody|Serpina6 antibody|Transcortin antibody

UniProt: P08185