SERPINC1 antibody (N-Term)

Catalog No. ABIN3042828

Product Details anti-SERPINC1 Antibody

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Binding Specificity: AA 93-107, N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINC1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Antithrombin-III(SERPINC1) detection. Tested with WB in Human,Mouse,Rat.

Sequence: TFYQHLADSK NDNDN

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Antithrombin-III(SERPINC1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: serpin peptidase inhibitor, clade C(antithrombin), member 1
Protein Name: Antithrombin-III

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Antithrombin III(93-107aa TFYQHLADSKNDNDN), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SERPINC1

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Alternative Name: SERPINC1 (SERPINC1 Products)

Synonyms: AT3 antibody, AT3D antibody, ATIII antibody, THPH7 antibody, SERPINC1 antibody, DKFZp470C1733 antibody, AI114908 antibody, At-3 antibody, At3 antibody, ANTITHROMBIN, AT-III antibody, AT-III antibody, serpin family C member 1 antibody, antithrombin-III antibody, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 antibody, SERPINC1 antibody, CpipJ_CPIJ000472 antibody, CpipJ_CPIJ013111 antibody, Serpinc1 antibody

Background: Serpin peptidase inhibitor, clade C(antithrombin), member 1, also known as Antithrombin III(AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases. This gene is mapped to 1q25.1. The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Synonyms: ANT3_HUMAN antibody|Antithrombin antibody|Antithrombin III antibody|Antithrombin-III antibody|AntithrombinIII antibody|AT 3 antibody|AT III antibody|AT3 antibody|AT3D antibody|ATIII antibody|MGC22579 antibody|Serine(or cysteine) proteinase inhibitor clade C(antithrombin) member 1 antibody|Serine cysteine proteinase inhibitor clade C member 1 antibody|Serine proteinase inhibitor clade C member 1 antibody|SERPIN C1 antibody|Serpin peptidase inhibitor clade C(antithrombin) member 1 antibody|SERPINC1 antibody|THPH7 antibody

UniProt: P01008