GLUT12 antibody (Middle Region)

Catalog No. ABIN3042856

Product Details anti-GLUT12 Antibody

Target: GLUT12 (SLC2A12) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 12 (SLC2A12))

Binding Specificity: AA 256-272, Middle Region

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLUT12 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 12(SLC2A12) detection. Tested with WB in Human,Mouse,Rat.

Sequence: SLKDEYQYSF WDLFRSK

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 12(SLC2A12) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: solute carrier family 2(facilitated glucose transporter), member 12
Protein Name: Solute carrier family 2, facilitated glucose transporter member 12

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human GLUT12(256-272aa SLKDEYQYSFWDLFRSK), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GLUT12

Target: GLUT12 (SLC2A12) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 12 (SLC2A12))

Alternative Name: SLC2A12 (SLC2A12 Products)

Synonyms: zgc:66027 antibody, zgc:85776 antibody, SLC2A12 antibody, GLUT12 antibody, GLUT8 antibody, GLUT-12 antibody, Glut12 antibody, glut12 antibody, solute carrier family 2 (facilitated glucose transporter), member 12 antibody, solute carrier family 2 member 12 antibody, solute carrier family 2 (facilitated glucose transporter), member 12 L homeolog antibody, slc2a12 antibody, SLC2A12 antibody, Slc2a12 antibody, slc2a12.L antibody

Background: Solute carrier family 2, facilitated glucose transporter member 12, also known as SLC2A12, is a protein that in humans is encoded by the SLC2A12 gene. SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion. This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues. By genomic sequence analysis, this gene is mapped to chromosome 6q23.2. SLC2A12 was detected in a perinuclear location in MCF7 cells in the absence of insulin, however, SLC2A12 redistributed to the plasma membrane of MCF7 cells grown continuously in the presence of insulin. This gene acts as facilitative glucose transporter.

Synonyms: Glucose transporter type 12 antibody|GLUT 12 antibody|GLUT-12 antibody|GLUT12 antibody|GLUT8 antibody|GTR12_HUMAN antibody|SLC2A12 antibody|Solute carrier family 2(facilitated glucose transporter) member 12 antibody|Solute carrier family 2 facilitated glucose transporter member 12 antibody|Solute carrier family 2 member 12 antibody|Solute carrier family 2, facilitated glucose transporter member 12 antibody

Pathways: Warburg Effect