ABCG4 antibody (Middle Region)

Catalog No. ABIN3042920

Product Details anti-ABCG4 Antibody

Target: ABCG4 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 (ABCG4))

Binding Specificity: AA 327-341, Middle Region

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCG4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 4(ABCG4) detection. Tested with WB in Human,Mouse,Rat.

Sequence: AVQNGLCAMA EKKSS

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 4(ABCG4) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ATP-binding cassette, sub-family G(WHITE), member 4
Protein Name: ATP-binding cassette sub-family G member 4

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ABCG4(327-341aa AVQNGLCAMAEKKSS), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ABCG4

Target: ABCG4 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 (ABCG4))

Alternative Name: ABCG4 (ABCG4 Products)

Synonyms: WHITE2 antibody, 6430517O04Rik antibody, zgc:171697 antibody, ATP binding cassette subfamily G member 4 antibody, ATP-binding cassette sub-family G member 4 antibody, ATP-binding cassette, sub-family G (WHITE), member 4a antibody, ATP-binding cassette, sub-family G (WHITE), member 4b antibody, ABCG4 antibody, CpipJ_CPIJ007191 antibody, CpipJ_CPIJ012365 antibody, CpipJ_CPIJ012372 antibody, CpipJ_CPIJ014443 antibody, CpipJ_CPIJ019125 antibody, CpipJ_CPIJ020198 antibody, PAAG_06842 antibody, Abcg4 antibody, LOC550918 antibody, abcg4a antibody, abcg4b antibody

Background: ABCG4(ATP-Binding Cassette, Subfamily G, Member 4), is a protein that in humans is encoded by the ABCG4 gene. The protein encoded by this gene is included in the superfamily of ATP-binding cassette(ABC) transporters. This protein is a member of the White subfamily and is expressed predominantly in liver tissue. By genomic sequence analysis, Engel et al.(2001) mapped the ABCG4 gene to chromosome 11q23.3. Engel et al.(2001) demonstrated 5-fold induction of ABCG4 following treatment of normal monocyte-derived macrophages with the LXR and RXR agonists 9-cis retinoic acid and 22R hydroxycholesterol. Removal of cholesterol from macrophages by cyclodextrin decreased ABCG4 message levels.

Synonyms: ABCG 4 antibody|ATP binding cassette subfamily G member 4 antibody|ATP-binding cassette, sub-family G(WHITE), member 4 antibody|Putative ABC transporter antibody|WHITE 2 antibody|WHITE2 antibody

UniProt: Q9H172