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PLA2G4A antibody (C-Term)

PLA2G4A Reactivity: Human, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042932
  • Target See all PLA2G4A Antibodies
    PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
    Binding Specificity
    • 28
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 686-700, C-Term
    Reactivity
    • 56
    • 33
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 65
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 69
    • 4
    Polyclonal
    Conjugate
    • 40
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLA2G4A antibody is un-conjugated
    Application
    • 59
    • 33
    • 19
    • 14
    • 14
    • 14
    • 11
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Cytosolic phospholipase A2(PLA2G4A) detection. Tested with WB in Human,Mouse,Rat.
    Sequence
    PNQAFKRLHD LMHFN
    Cross-Reactivity (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Characteristics
    Rabbit IgG polyclonal antibody for Cytosolic phospholipase A2(PLA2G4A) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: phospholipase A2, group IVA(cytosolic, calcium-dependent)
    Protein Name: Cytosolic phospholipase A2
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human PLA2G4A (686-700aa PNQAFKRLHDLMHFN), different from the related rat and mouse sequences by one amino acid.
    Isotype
    IgG
    Top Product
    Discover our top product PLA2G4A Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for PLA2G4A is approximately 0.5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
  • Target
    PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))
    Alternative Name
    PLA2G4A (PLA2G4A Products)
    Synonyms
    PLA2G4 antibody, cPLA2-alpha antibody, Pla2c antibody, Pla2g4 antibody, cPLA2 antibody, pla2g4 antibody, CPLA2 antibody, PLA2G4A antibody, PLA2 antibody, PLA2G1B antibody, cPLA2alpha antibody, pla2g4a antibody, si:dkey-97o5.1 antibody, phospholipase A2 group IVA antibody, phospholipase A2 group IVA L homeolog antibody, phospholipase A2, group IVA (cytosolic, calcium-dependent) antibody, phospholipase A2, group IVAb (cytosolic, calcium-dependent) antibody, PLA2G4A antibody, Pla2g4a antibody, pla2g4a.L antibody, pla2g4ab antibody
    Background
    PLA2G4A(Phospholipase A2, Group IVA), is an enzyme that in humans is encoded by the PLA2G4A gene. Tay et al.(1995) mapped the PLA2G4A gene to rat chromosome 13 by PCR-based intercross genotyping and to human 1q25 by fluorescence in situ hybridization. By site-directed mutagenesis and biochemical analysis of the recombinant protein, Sharp et al.(1994) determined that ser228 participates in the catalytic mechanism of cPLA2 and that both the phospholipase A2 and the lysophospholipase activities are catalyzed by the same active site residue(s). PLA2G4A, the cytosolic phospholipase A2, appears to subserve transmembrane signaling responses to extracellular ligands(Skorecki, 1995).

    Synonyms: Calcium dependent phospholipid binding protein antibody|CPLA 2 antibody|cPLA2 alpha antibody|cPLA2 antibody|Cytosolic phospholipase A2 antibody|Cytosolic phospholipase A2 group IVA antibody|Lysophospholipase antibody|MGC126350 antibody|PA24A_HUMAN antibody|Phosphatidylcholine 2 acylhydrolase antibody|Phosphatidylcholine 2-acylhydrolase antibody|Phospholipase A2 group 4 A antibody|Phospholipase A2 group IVA(cytosolic calcium dependent) antibody|Phospholipase A2 group IVA antibody|PhospholipaseA2 antibody|PLA2G4 antibody|pla2g4a antibody
    UniProt
    P47712
    Pathways
    Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling
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