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DISC1 antibody (N-Term)

DISC1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042946
  • Target See all DISC1 Antibodies
    DISC1 (Disrupted in Schizophrenia 1 (DISC1))
    Binding Specificity
    • 15
    • 14
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 74-91, N-Term
    Reactivity
    • 71
    • 25
    • 14
    • 1
    Human
    Host
    • 70
    • 4
    • 1
    • 1
    Rabbit
    Clonality
    • 72
    • 6
    Polyclonal
    Conjugate
    • 43
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DISC1 antibody is un-conjugated
    Application
    • 48
    • 31
    • 26
    • 14
    • 14
    • 11
    • 11
    • 8
    • 6
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Disrupted in schizophrenia 1 protein(DISC1) detection. Tested with WB in Human.
    Sequence
    EESHHSESRA RQCGLDSR
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Disrupted in schizophrenia 1 protein(DISC1) detection. Tested with WB in Human.
    Gene Name: disrupted in schizophrenia 1
    Protein Name: Disrupted in schizophrenia 1 protein
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human DISC1(74-91aa EESHHSESRARQCGLDSR).
    Isotype
    IgG
    Top Product
    Discover our top product DISC1 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
  • Target
    DISC1 (Disrupted in Schizophrenia 1 (DISC1))
    Alternative Name
    DISC1 (DISC1 Products)
    Synonyms
    DISC1 antibody, C1orf136 antibody, SCZD9 antibody, disrupted in schizophrenia 1 antibody, disrupted in schizophrenia 1 protein antibody, disc1 antibody, DISC1 antibody, LOC100580606 antibody, Disc1 antibody
    Background
    DISC1(Disrupted in Schizophrenia 1), is a protein that is encoded by the DISC1 gene in humans. Ma et al.(2002) determined that the mouse Disc1 gene maps to chromosome 8 in a region with homology of synteny to human chromosome 1q42. Ozeki et al.(2003) demonstrated that rodent Disc1 expression displayed pronounced developmental regulation, with the highest levels in late embryonic life during development of the cerebral cortex. Millar et al.(2005) showed that DISC1 interacts with the UCR2 domain of phosphodiesterase-4B, implicated in susceptibility to schizophrenia, and that elevation of cellular cAMP leads to dissociation of PDE4B from DISC1 and in increase in PDE4B activity.

    Synonyms: C1orf136 antibody|DISC1 antibody|DISC1_HUMAN antibody|Disrupted in schizophrenia 1 antibody|Disrupted in schizophrenia 1 protein antibody|KIAA0457 antibody|RP4-730B13.1 antibody|SCZD9 antibody
    Pathways
    Regulation of Cell Size
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