DR3/LARD antibody (N-Term)

Catalog No. ABIN3042955

Product Details anti-DR3/LARD Antibody

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Binding Specificity: AA 73-94, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DR3/LARD antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 25(TNFRSF25) detection. Tested with WB in Human.

Sequence: CPQDTFLAWE NHHNSECARC QA

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 25(TNFRSF25) detection. Tested with WB in Human.
Gene Name: tumor necrosis factor receptor superfamily, member 25
Protein Name: Tumor necrosis factor receptor superfamily member 25

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human DR3(73-94aa CPQDTFLAWENHHNSECARCQA).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TNFRSF25 is approximately 3 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DR3/LARD

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Alternative Name: TNFRSF25 (TNFRSF25 Products)

Synonyms: APO-3 antibody, DDR3 antibody, DR3 antibody, LARD antibody, TNFRSF12 antibody, TR3 antibody, TRAMP antibody, WSL-1 antibody, WSL-LR antibody, Tnfrsf12 antibody, Wsl antibody, TNFRSF25 antibody, TNF receptor superfamily member 25 antibody, tumor necrosis factor receptor superfamily, member 25 antibody, TNFRSF25 antibody, Tnfrsf25 antibody

Background: TNFRSF25(Tumor Necrosis Factor Receptor Superfamily Member 25), also known as LARD, APO3, DR3 or TNFR25, is a protein that in humans is encoded by the TNFRSF25 gene. Members of the mammalian tumor necrosis factor receptor(TNFR) family are cell-surface proteins that interact with a corresponding TNF-related ligand family. By fluorescence in situ hybridization, Marsters et al.(1996) mapped the Apo3 gene to 1p36.3. Marsters et al.(1996) showed that ectopic expression of Apo3 in mammalian cells triggered apoptosis and activated the transcription factor NF-kappa-B. They suggested that, like TNFR1, Apo3 may regulate distinct signaling pathways in different cellular contexts.

Synonyms: Apo 3 antibody|Apo-3 antibody|Apo3 antibody|Apoptosis inducing receptor AIR antibody|Apoptosis inducing receptor antibody|Apoptosis mediating receptor antibody|Apoptosis mediating receptor DR 3 antibody|Apoptosis mediating receptor DR3 antibody|Apoptosis mediating receptor TRAMP antibody|Apoptosis-inducing receptor AIR antibody|Apoptosis-mediating receptor DR3 antibody|Apoptosis-mediating receptor TRAMP antibody|DDR 3 antibody|DDR3 antibody|Death domain receptor 3 antibody|Death Receptor 3 antibody|Death receptor beta antibody|DR 3 antibody|LARD antibody|Lymphocyte associated receptor of death antibody|Lymphocyte-associated receptor of death antibody|Protein WSL antibody|Protein WSL-1 antibody|TNFRSF 12 antibody|TNFRSF 25 antibody|TNFRSF12 antibody|TNFRSF25 antibody|TNR25_HUMAN antibody|TR 3 antibody|TR3 antibody|TRAMP antibody|Translocating chain association membrane protein antibody|Tumor necrosis factor receptor superfamily member 12 antibody|Tumor necrosis factor receptor superfamily member 25 antibody|WSL 1 antibody|WSL antibody|WSL LR antibody|WSL protein antibody|WSL1 antibody|WSL1 protein antibody|WSLLR antibody

UniProt: Q93038

Pathways: Apoptosis