IL5RA antibody (N-Term)

Catalog No. ABIN3043143

Product Details anti-IL5RA Antibody

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Binding Specificity: AA 53-68, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL5RA antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Interleukin-5 receptor subunit alpha(IL5RA) detection. Tested with WB in Human.

Sequence: NPDQEQRNVN LEYQVK

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Interleukin-5 receptor subunit alpha(IL5RA) detection. Tested with WB in Human.
Gene Name: interleukin 5 receptor, alpha
Protein Name: Interleukin-5 receptor subunit alpha(IL-5 receptor subunit alpha/IL-5R subunit alpha/IL-5R-alpha/IL-5RA)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human IL5RA(53-68aa NPDQEQRNVNLEYQVK).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL5RA

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Alternative Name: IL5RA (IL5RA Products)

Synonyms: MGC86517 antibody, IL5RA antibody, il5r antibody, cdw125 antibody, hsil5r3 antibody, gpIL-5ra antibody, CD125 antibody, CDw125 antibody, HSIL5R3 antibody, IL5R antibody, Il5r antibody, interleukin 5 receptor subunit alpha L homeolog antibody, interleukin 5 receptor subunit alpha antibody, interleukin 5 receptor, alpha antibody, il5ra.L antibody, IL5RA antibody, il5ra antibody, Il5ra antibody

Background: IL5RA(INTERLEUKIN 5 RECEPTOR, ALPHA), also known as CD125, is a subunit of the Interleukin-5 receptor. IL5RA also denotes its human gene. The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2(CSF2/GM-CSF), and interleukin 5(IL5). The IL5RA gene is mapped to 3p26-p24 by Southern blot analysis of DNA from a panel of mouse-human hybrid somatic cell lines complemented by in situ hybridization. And its Cytogenetic location is 3p26.2. Within this 15-residue stretch of IL5RA, the C-terminal phenylalanine is critical. The binding of this protein to IL5 depends on the beta subunit which is activated by the ligand binding and is required for the biological activities of IL5.

Synonyms: CD125 antibody|CD125 antigen antibody|CDw125 antibody|HSIL5R3 antibody|IL-5 receptor subunit alpha antibody|IL-5R subunit alpha antibody|IL-5R-alpha antibody|IL-5RA antibody|IL5R antibody|IL5RA antibody|IL5RA_HUMAN antibody|Interleukin 5 Receptor alpha antibody|Interleukin 5 Receptor alpha chain antibody|Interleukin 5 receptor alpha subunit antibody|Interleukin 5 receptor subunit alpha antibody|Interleukin 5 receptor type 3 antibody|Interleukin-5 receptor subunit alpha antibody|MGC26560 antibody

UniProt: Q01344

Pathways: JAK-STAT Signaling