IGFBPI antibody (Middle Region)

Catalog No. ABIN3043191

Product Details anti-IGFBPI Antibody

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Binding Specificity: AA 170-190, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBPI antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 1(IGFBP1) detection. Tested with WB in Human.

Sequence: KEPCRIELYR VVESLAKAQE T

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Insulin-like growth factor-binding protein 1(IGFBP1) detection. Tested with WB in Human.
Gene Name: insulin-like growth factor binding protein 1
Protein Name: Insulin-like growth factor-binding protein 1(IBP-1/IGF-binding protein 1/IGFBP-1)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human IGFBP-1(170-190aa KEPCRIELYRVVESLAKAQET).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IGFBPI

Target: IGFBPI (Insulin-Like Growth Factor Binding Protein 1 (IGFBPI))

Alternative Name: IGFBP1 (IGFBPI Products)

Synonyms: cb656 antibody, igfbp1 antibody, IGFBP-1 antibody, MGC68538 antibody, afbp antibody, ibp1 antibody, pp12 antibody, igf-bp25 antibody, higfbp-1 antibody, IGFBP1 antibody, LOC100223208 antibody, LOC100305121 antibody, AFBP antibody, IBP1 antibody, IGF-BP25 antibody, PP12 antibody, hIGFBP-1 antibody, IGFBA antibody, insulin like growth factor binding protein 1 antibody, insulin-like growth factor binding protein 1a antibody, insulin like growth factor binding protein 1 S homeolog antibody, insulin like growth factor binding protein 1 L homeolog antibody, insulin-like growth factor binding protein 1 antibody, IGFBP1 antibody, igfbp1a antibody, igfbp1.S antibody, igfbp1.L antibody, igfbp1 antibody, LOC100305121 antibody, Igfbp1 antibody

Background: IGFBP1, Insulin-like growth factor-binding protein 1, also known as placental protein 12(PP12), is a protein that in humans is encoded by the IGFBP1 gene. The IGFBP1 gene has 4 exons and spans 5.9 kb. The IGFBP1gene is localized to 7p13-p12 by in situ hybridization. This gene is a member of the Insulin-like growth factor-binding protein(IGFBP) family and encodes a protein with an IGFBP domain and a type-I thyroglobulin domain. The protein binds both insulin-like growth factors(IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms: AFBP antibody|Alpha pregnancy associated endometrial globulin antibody|Amniotic fluid binding protein antibody|Binding protein 25 antibody|Binding protein 26 antibody|Binding protein 28 antibody|Growth hormone independent binding protein antibody|hIGFBP 1 antibody|hIGFBP1 antibody|IBP 1 antibody|IBP-1 antibody|IBP1 antibody|IBP1_HUMAN antibody|IGF binding protein 1 antibody|IGF BP25 antibody|IGF-binding protein 1 antibody|IGFBP 1 antibody|IGFBP-1 antibody|IGFBP1 antibody|Insulin Like Growth Factor Binding Protein 1 antibody|Insulin-like growth factor-binding protein 1 antibody|Placental protein 12 antibody|PP 12 antibody|PP12 antibody

UniProt: P08833

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Growth Factor Binding