NEDD9 antibody (AA 273-421)

Catalog No. ABIN3043271

Product Details anti-NEDD9 Antibody

Target: NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))

Binding Specificity: AA 273-421

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEDD9 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Enhancer of filamentation 1(NEDD9) detection. Tested with WB in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Enhancer of filamentation 1(NEDD9) detection. Tested with WB in Human.
Gene Name: neural precursor cell expressed, developmentally down-regulated 9
Protein Name: Enhancer of filamentation 1

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HEF1 recombinant protein (Position: K273-E421). Human HEF1 shares 83% amino acid (aa) sequence identity with mouse HEF1.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for HEF1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for NEDD9

Target: NEDD9 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9))

Alternative Name: NEDD9 (NEDD9 Products)

Synonyms: NEDD9 antibody, CAS-L antibody, CAS2 antibody, CASL antibody, CASS2 antibody, HEF1 antibody, Cas-L antibody, CasL antibody, E230025G09Rik antibody, neural precursor cell expressed, developmentally down-regulated 9 antibody, neural precursor cell expressed, developmentally down-regulated gene 9 antibody, NEDD9 antibody, Nedd9 antibody

Background: Enhancer of filamentation 1 (EF1), also known as NEDD-9, is a protein that in humans is encoded by the NEDD9 gene. The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. It is mapped to 6p24.2. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. NEDD9 is also a highly relevant cancer gene that governs metastatic potential in human melanoma. What's more, it has been speculated that NEDD9 may be an important linking element between extracellular signaling and regulation of the cytoskeleton.

Synonyms: CAS L antibody|Cas like docking antibody|Cas scaffolding protein family member 2 antibody|CAS-L antibody|CAS2 antibody|CASL antibody|CASL_HUMAN antibody|CASS2 antibody|Crk associated substrate related antibody|Crk associated substrate related protein antibody|CRK-associated substrate-related protein antibody|dJ49G10.2 (Enhancer of Filamentation 1 (HEF1)) antibody|dJ49G10.2 antibody|dJ761I2.1 (enhancer of filamentation (HEF1)) antibody|dJ761I2.1 antibody|Enhancer of filamentation 1 antibody|Enhancer of filamentation 1 p55 antibody|HEF 1 antibody|HEF1 antibody|NEDD 9 antibody|NEDD-9 antibody|NEDD9 antibody|NEDD9 protein antibody|Neural cell expressed developmentally down regulated 9 antibody|Neural precursor cell expressed developmentally down regulated 9 antibody|Neural precursor cell expressed developmentally down-regulated protein 9 antibody|NY REN 12 antigen antibody|p105 antibody|Protein NEDD9 antibody|Renal carcinoma antigen NY-REN-12 antibody

Gene ID: 4739

UniProt: Q14511