STRAP antibody (N-Term)

Catalog No. ABIN3043302

Product Details anti-STRAP Antibody

Target: STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))

Binding Specificity: AA 78-104, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Serine-threonine kinase receptor-associated protein(STRAP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequence: AADFTAKVWD AVSGDELMTL AHKHIVK

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Serine-threonine kinase receptor-associated protein(STRAP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: serine/threonine kinase receptor associated protein
Protein Name: Serine-threonine kinase receptor-associated protein

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Unrip(78-104aa AADFTAKVWDAVSGDELMTLAHKHIVK), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat , The detection limit for Unrip is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for STRAP

Target: STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))

Alternative Name: STRAP (STRAP Products)

Synonyms: MAWD antibody, PT-WD antibody, UNRIP antibody, zgc:56677 antibody, zgc:77604 antibody, mawd antibody, pt-wd antibody, unrip antibody, AW557906 antibody, C78091 antibody, C79202 antibody, Unrip antibody, serine/threonine kinase receptor associated protein antibody, tetratricopeptide repeat domain 5 antibody, serine/threonine kinase receptor associated protein L homeolog antibody, serine/threonine kinase receptor associated protein S homeolog antibody, STRAP antibody, TTC5 antibody, strap antibody, strap.L antibody, strap.S antibody, Strap antibody

Background: Unrip is also known as STRAP(Serine-threonine kinase receptor-associated protein). It is anenzyme that in humans is encoded by the STRAP gene. It is mapped to 12p12.3. UNRIP is integrated into a complex with UNR or with the SMN complex in vivo in a mutually exclusive manner. It is concluded that UNRIP is the first component of the uridine-rich snRNP assembly machinery that associates with the SMN complex in a compartment-specific way, and it may play a crucial role in the intracellular distribution of the SMN complex.

Synonyms: MAP activator with WD repeats antibody|MAWD antibody|PT-WD antibody|PTWD antibody|Serine-threonine kinase receptor-associated protein antibody|serine/threonine kinase receptor associated protein antibody|STRAP antibody|STRAP_HUMAN antibody|unr interacting protein antibody|unr-interacting protein antibody|UNRIP antibody|WD 40 repeat protein PT WD antibody|WD-40 repeat protein PT-WD antibody

Gene ID: 11171

UniProt: Q9Y3F4