SDC4 antibody (C-Term)

Catalog No. ABIN3043323

Product Details anti-SDC4 Antibody

Target: SDC4 (Syndecan 4 (SDC4))

Binding Specificity: AA 172-198, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Syndecan-4(SDC4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequence: MKKKDEGSYD LGKKPIYKKA PTNEFYA

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Syndecan-4(SDC4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: syndecan 4
Protein Name: Syndecan-4

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Syndecan 4 (172-198aa MKKKDEGSYDLGKKPIYKKAPTNEFYA), identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat , The detection limit for Syndecan 4 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for SDC4

Target: SDC4 (Syndecan 4 (SDC4))

Alternative Name: SDC4 (SDC4 Products)

Synonyms: SYND4 antibody, AA959608 antibody, AW108331 antibody, Synd4 antibody, ryudocan antibody, syndecan-4 antibody, RATRYUDOCA antibody, RYUDOCA antibody, SDC4 antibody, sdc4l antibody, wu:fc47g09 antibody, Syndecan-4 antibody, amphiglycan antibody, syn-4 antibody, syn4 antibody, syndecan 4 antibody, syndecan 4 S homeolog antibody, syndecan 4 L homeolog antibody, SDC4 antibody, Sdc4 antibody, sdc4 antibody, sdc4.S antibody, sdc4.L antibody

Background: Syndecan 4 is also known as SDC4. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Synonyms: Amphiglycan antibody|Amphiglycan antibody|MGC22217 antibody|OTTHUMP00000031788 antibody|ryudocan amphiglycan antibody|Ryudocan antibody|Ryudocan core protein antibody|Ryudocan core protein antibody|SDC 4 antibody|SDC4 antibody|SDC4_HUMAN antibody|SYND 4 antibody|SYND4 antibody|syndecan 4 antibody|syndecan 4 (amphiglycan, ryudocan) antibody|syndecan proteoglycan 4 antibody|Syndecan-4 antibody|Syndecan4 antibody

Gene ID: 6385

UniProt: P31431

Pathways: Glycosaminoglycan Metabolic Process