SDHA antibody (AA 44-380)

Catalog No. ABIN3043324

Product Details anti-SDHA Antibody

Target: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Binding Specificity: AA 44-380

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDHA antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Protein Name: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SDHA recombinant protein (Position: S44-L380). Human SDHA shares 98.2% and 97.6% amino acid (aa) sequence identity with mouse and rat SDHA, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for SDHA

Target: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Alternative Name: SDHA (SDHA Products)

Synonyms: CG17246 antibody, Dmel\\CG17246 antibody, Scs-fp antibody, Sdh antibody, Sdha antibody, scs-fp antibody, sdh antibody, CMD1GG antibody, FP antibody, PGL5 antibody, SDH1 antibody, SDH2 antibody, SDHF antibody, 1500032O14Rik antibody, 2310034D06Rik antibody, 4921513A11 antibody, C81073 antibody, im:7141001 antibody, zgc:56051 antibody, Fp antibody, sdha-b antibody, Succinate dehydrogenase, subunit A (flavoprotein) antibody, succinate dehydrogenase complex flavoprotein subunit A antibody, succinate dehydrogenase complex, subunit A, flavoprotein (Fp) antibody, succinate dehydrogenase complex subunit A, flavoprotein (Fp) S homeolog antibody, SdhA antibody, SDHA antibody, Sdha antibody, sdha antibody, sdha.S antibody

Background: Complex II of the mitochondrial respiratory chain, also known as succinate dehydrogenase or succinate:ubiquinone oxidoreductase, consists of 4 nuclear-encoded polypeptides, these are the flavoprotein subunit (SDHA), the iron sulfur protein subunit (SDHB), and the integral membrane protein subunits SDHC and SDHD. SDHA is an acronym for succinate dehydrogenase complex subunit A. The succinate dehydrogenase (SDH) protein complex catalyzes the oxidation of succinate (succinate + ubiquinone => fumarate + ubiquinol). The SDHA subunit is connected to the SDHB subunit on the hydrophilic, catalytic end of the complex, and weighs 72.7 kDA. Mutations in the SDHA subunit have a distinct pathology from mutations in the SDHB/SDHC/SDHD subunits, it is the only subunit to never have shown tumor suppressor behaviour. Heterozygous carriers of an SDHA mutation do not develop paragangliomas as has been seen for mutations in the other subunits. This appears to be due to the expression of two similar SDHA genes (Types I and II) in the paraganglia system.

Synonyms: MD1GG antibody|DHSA_HUMAN antibody|Flavoprotein subunit of complex II antibody|FP antibody| PGL5 antibody|SDH 2 antibody|SDH1 antibody|SDH2 antibody|SDHA antibody|SDHF antibody| Succinate dehydrogenase [ubiquinone] flavoprotein subunit antibody|Succinate dehydrogenase [ubiquinone] flavoprotein subunit mitochondrial antibody|Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial antibody|Succinate dehydrogenase complex flavoprotein subunit antibody|Succinate dehydrogenase complex flavoprotein subunit precursor antibody|Succinate dehydrogenase complex subunit A antibody| Succinate dehydrogenase complex subunit A flavoprotein antibody

Gene ID: 6389

UniProt: P31040