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SGK1 antibody (N-Term)

SGK1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043433
  • Target See all SGK1 Antibodies
    SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
    Binding Specificity
    • 20
    • 20
    • 16
    • 14
    • 9
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-55, N-Term
    Reactivity
    • 138
    • 94
    • 76
    • 20
    • 17
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 123
    • 11
    • 4
    • 1
    Rabbit
    Clonality
    • 127
    • 12
    Polyclonal
    Conjugate
    • 66
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    This SGK1 antibody is un-conjugated
    Application
    • 131
    • 57
    • 50
    • 44
    • 40
    • 29
    • 28
    • 22
    • 9
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase Sgk1(SGK1) detection. Tested with WB in Human.
    Sequence
    MKQRRMGLND FIQKIANNSY ACKHPEVQ
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase Sgk1(SGK1) detection. Tested with WB in Human.
    Gene Name: serum/glucocorticoid regulated kinase 1
    Protein Name: Serine/threonine-protein kinase Sgk1
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human SGK1 (28-55aa MKQRRMGLNDFIQKIANNSYACKHPEVQ), different from the related mouse sequence by three amino acids, and from the related rat sequence by one amino acid.
    Isotype
    IgG
    Top Product
    Discover our top product SGK1 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SGK1 is approximately 0.1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Chang, Bok, Sun, Edwards, Huang: "Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress." in: PLoS genetics, Vol. 12, Issue 10, pp. e1006356, (2017) (PubMed).

  • Target
    SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
    Alternative Name
    SGK1 (SGK1 Products)
    Synonyms
    SGK antibody, Sgk antibody, sgk-B antibody, sgk2 antibody, cb1083 antibody, sgk antibody, wu:fc20a09 antibody, sgk-A antibody, sgk1 antibody, sgk1-a antibody, sgk1-b antibody, serum/glucocorticoid regulated kinase 1 antibody, Serine/threonine-protein kinase sgk-1 antibody, serum/glucocorticoid regulated kinase 1 S homeolog antibody, serum/glucocorticoid regulated kinase 1 L homeolog antibody, SGK1 antibody, Sgk1 antibody, sgk-1 antibody, sgk1.S antibody, sgk1 antibody, sgk1.L antibody
    Background
    Serine/threonine-protein kinase Sgk1, also called SGK1, encodes a serine/threonine protein kinase that plays an important role in cellular stress response. By fluorescence in situ hybridization, this gene is mapped to 6q23.2. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

    Synonyms: Serine/threonine protein kinase SGK antibody|Serine/threonine protein kinase Sgk1 antibody| Serine/threonine-protein kinase Sgk1 antibody|Serum and glucocorticoid regulated kinase antibody|Serum/glucocorticoid regulated kinase 1 antibody|Serum/glucocorticoid regulated kinase antibody|Serum/glucocorticoid-regulated kinase 1 antibody|SGK 1 antibody|SGK antibody|SGK1 antibody|SGK1_HUMAN antibody
    Gene ID
    6446
    UniProt
    O00141
    Pathways
    MAPK Signaling, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
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