TRPC7 antibody (AA 716-862)

Catalog No. ABIN3043494

Product Details anti-TRPC7 Antibody

Target: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Binding Specificity: AA 716-862

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPC7 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Short transient receptor potential channel 7(TRPC7) detection. Tested with WB in Human,Mouse.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Short transient receptor potential channel 7(TRPC7) detection. Tested with WB in Human,Mouse.
Gene Name: transient receptor potential cation channel, subfamily C, member 7
Protein Name: Short transient receptor potential channel 7

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRP 7 recombinant protein (Position: K716-I862). Human TRP 7 shares 95% amino acid (aa) sequence identity with mouse TRP 7.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, The detection limit for TRP 7 is approximately 0.2 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-TRPC7 antibody (ABIN3043494)

Wang, Wang, Li: "TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells." in: Oncotarget, Vol. 7, Issue 32, pp. 50937-50951, (2018) (PubMed).

Target Details for TRPC7

Target: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Alternative Name: TRPC7 (TRPC7 Products)

Synonyms: TRP7 antibody, TRP-7 antibody, Trrp8 antibody, TRPC7 antibody, TRPM2 antibody, transient receptor potential cation channel subfamily C member 7 antibody, transient receptor potential cation channel, subfamily C, member 7 antibody, short transient receptor potential channel 7 antibody, TRPC7 antibody, Trpc7 antibody, LOC100012798 antibody

Background: Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name. Using a cosmid/BAC contig, this gene is mapped to chromosome 21q22.3. TRPC7 is the most abundantly expressed long TRPC in peripheral blood and in some blood cell lines. The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.

Synonyms: Capacitative calcium channel TRPC7 antibody|cation channel, subfamily C, member 7 antibody|hTRP7 antibody|KNP3 antibody|Likley ortholog of mouse transient receptor potential cation channel subfamily C member 7 antibody|mTRP7 antibody|Putative capacitative calcium channel antibody|Short transient receptor potential channel 7 antibody|Transient receptor potential cation channel subfamily C member 7 antibody|transient receptor potential-related channel 7, a novel putative Ca2+ channel protein antibody|Transient receptor protein 7 antibody|TRP 7 antibody|TRP-7 antibody|TRP7 protein antibody|TRPC 7 antibody|TRPC7 antibody|Trpc7 transient receptor potential cation channel, subfamily C, member 7 antibody|TRPC7_HUMAN antibody|TRPM2 antibody|Trrp8 antibody

Gene ID: 57113