Prolactin antibody (AA 30-226)

Catalog No. ABIN3043552

Product Details anti-Prolactin Antibody

Target: Prolactin (PRL)

Binding Specificity: AA 30-226

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prolactin antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Prolactin(PRL) detection. Tested with WB, ELISA in Mouse.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Prolactin(PRL) detection. Tested with WB, ELISA in Mouse.
Gene Name: prolactin
Protein Name: Prolactin

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Prolactin recombinant protein (Position: L30-C226). Mouse Prolactin shares 59.8% and 84.8% amino acid (aa) sequence identity with human and rat Prolactin, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse , The detection limit for Prolactin is approximately 0.2 ng/lane under reducing conditions.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Prolactin antibody (ABIN3043552)

Wang, Tan, Ma, Liang, Zhang, Tan, Wang, Luo: "Positive Regulation of Decidualization by l-Type Amino Acid Transporter 1 (lat1) in Pregnant Mice." in: Nutrients, Vol. 8, Issue 11, (2017) (PubMed).

Huang, Cao, Liu, Zou, Li, Yin: "MAPK/ERK signal pathway involved expression of COX-2 and VEGF by IL-1β induced in human endometriosis stromal cells in vitro." in: International journal of clinical and experimental pathology, Vol. 6, Issue 10, pp. 2129-36, (2014) (PubMed).

Huang, Wang, Zou, Liu, Cao, Yin: "Effect of GnRH-II on the ESC proliferation, apoptosis and VEGF secretion in patients with endometriosis in vitro." in: International journal of clinical and experimental pathology, Vol. 6, Issue 11, pp. 2487-96, (2013) (PubMed).

Target Details for Prolactin

Target: Prolactin (PRL)

Alternative Name: PRL (PRL Products)

Synonyms: PRL antibody, prolactin antibody, PRLB antibody, PRLSD1 antibody, Prl1a1 antibody, Prol antibody, RATPRLSD1 antibody, RNPROL antibody, AV290867 antibody, prl antibody, prolactin antibody, prolactin, gene 2 L homeolog antibody, PROLACTIN protein antibody, prolactin-like antibody, PRL antibody, prl.2.L antibody, Prl antibody, LOC100136792 antibody, LOC100136580 antibody, PROLACTIN antibody, LOC101843376 antibody

Background: Prolactin (PRL) also known as luteotropic hormone (LTH) is a protein that in humans is encoded by the PRL gene. Prolactin is a peptide hormone discovered by Henry Friesen. Although it is perhaps best known for its role in lactation, prolactin already existed in the oldest known vertebrates-fishes-where its most important functions were probably related to control of water and salt balance. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. Prolactin has important cell cycle related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor binding to cytokine like receptors it has also profound influence on hematopoiesis, angiogenesis and is involved in the regulation of blood clotting through several pathways.

Synonyms: Decidual prolactin antibody|Lactogenic Hormone antibody|Luteotropic Hormone antibody|Mammotropin antibody|PRL antibody|Prolactin antibody|Prolactin precursor antibody

Gene ID: 19109

UniProt: P06879

Pathways: JAK-STAT Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus