NLRC4 antibody (C-Term)
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- Target See all NLRC4 Antibodies
- NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
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Binding Specificity
- AA 838-874, C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NLRC4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for NLR family CARD domain-containing protein 4(NLRC4) detection. Tested with WB in Human,Mouse,Rat.
- Sequence
- KILAQNLHNL VKLSILDLSE NYLEKDGNEA LHELIDR
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for NLR family CARD domain-containing protein 4(NLRC4) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: NLR family, CARD domain containing 4
Protein Name: NLR family CARD domain-containing protein 4 - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human CARD12 (838-874aa KILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDR), different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NLRC4 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
- Alternative Name
- NLRC4 (NLRC4 Products)
- Synonyms
- CARD12 antibody, CLAN antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR2.1 antibody, IPAF antibody, 9530011P19Rik antibody, Card12 antibody, NLR family CARD domain containing 4 antibody, NLR family, CARD domain containing 4 antibody, NLRC4 antibody, Nlrc4 antibody
- Background
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NLR family CARD domain-containing protein 4, also known as CARD12, is a protein that in humans is encoded by the NLRC4 gene. It is mapped to 2p22.3. This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.
Synonyms: and NACHT-containing protein antibody|CARD 12 antibody|CARD antibody|CARD LRR and NACHT containing protein 1 antibody|CARD LRR and NACHT containing protein antibody|CARD12 antibody|Caspase recruitment domain containing protein 12 antibody|Caspase recruitment domain family member 12 antibody|Caspase recruitment domain-containing protein 12 antibody|CLAN 1 antibody|CLAN A antibody|CLAN antibody|CLAN B antibody|CLAN C antibody|CLAN D antibody|Clan protein antibody|CLAN1 antibody|CLANA antibody|CLANB antibody|CLANC antibody| CLAND antibody|CLR 2.1 antibody|CLR2.1 antibody|ICE protease activating factor antibody|Ice protease-activating factor antibody|IPAF antibody|LRR antibody|NLR family CARD domain containing 4 antibody|NLR family CARD domain-containing protein 4 antibody|NLRC 4 antibody|NLRC4 antibody|NLRC4_HUMAN antibody|NOD like receptor C4 antibody|Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 4 antibody|UNQ6189/PRO20215 antibody - Gene ID
- 58484
- Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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