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FXYD1 antibody (AA 21-92)

FXYD1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043831
  • Target See all FXYD1 Antibodies
    FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))
    Binding Specificity
    • 16
    • 15
    • 15
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 21-92
    Reactivity
    • 67
    • 31
    • 12
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 72
    • 13
    Rabbit
    Clonality
    • 72
    • 13
    Polyclonal
    Conjugate
    • 17
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    This FXYD1 antibody is un-conjugated
    Application
    • 73
    • 39
    • 39
    • 28
    • 9
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Phospholemman(FXYD1) detection. Tested with WB, IHC-P in Human,Rat,Mouse.
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Phospholemman(FXYD1) detection. Tested with WB, IHC-P in Human,Rat,Mouse.
    Gene Name: FXYD domain containing ion transport regulator 1
    Protein Name: Phospholemman
    Purification
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human FXYD1 recombinant protein (Position: E21-R92). Human FXYD1 shares 86.1% and 87.5% amino acid (aa) sequence identity with mouse and rat FXYD1, respectively.
    Isotype
    IgG
    Top Product
    Discover our top product FXYD1 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    FXYD1 (FXYD Domain Containing Ion Transport Regulator 1 (FXYD1))
    Alternative Name
    FXYD1 (FXYD1 Products)
    Synonyms
    PLM antibody, 0610012C17Rik antibody, 1110006M24Rik antibody, Plm antibody, Pml antibody, FXYD domain containing ion transport regulator 1 antibody, FXYD domain-containing ion transport regulator 1 antibody, FXYD1 antibody, Fxyd1 antibody
    Background
    Phospholemman is a protein that in humans is encoded by the FXYD1 gene. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. Transcript variants with different 5' UTR sequences have been described in the literature.

    Synonyms: FXYD domain containing ion transport regulator 1 antibody|Phospholemman antibody|PLM antibody
    Gene ID
    5348
    UniProt
    O00168
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