SLC1A4 antibody (C-Term)

Catalog No. ABIN3044002

Product Details anti-SLC1A4 Antibody

Target: SLC1A4 (Solute Carrier Family 1 (Glutamate/Neutral Amino Acid Transporter), Member 4 (SLC1A4))

Binding Specificity: AA 495-512, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC1A4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Neutral amino acid transporter A(SLC1A4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequence: EAIPNCKSEE ETSPLVTH

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Neutral amino acid transporter A(SLC1A4) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: solute carrier family 1(glutamate/neutral amino acid transporter), member 4
Protein Name: Neutral amino acid transporter A

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC1A4(495-512aa EAIPNCKSEEETSPLVTH), different from the related rat and mouse sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SLC1A4

Target: SLC1A4 (Solute Carrier Family 1 (Glutamate/Neutral Amino Acid Transporter), Member 4 (SLC1A4))

Alternative Name: SLC1A4 (SLC1A4 Products)

Synonyms: satt antibody, asct1 antibody, si:zc101n13.5 antibody, zgc:92817 antibody, ASCT1 antibody, SATT antibody, ASCT-1 antibody, AW045657 antibody, solute carrier family 1 member 4 antibody, solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 antibody, SLC1A4 antibody, slc1a4 antibody, Slc1a4 antibody

Background: Neutral amino acid transporter A, also called SLC1A4 or ASCT1, is a protein that in humans is encodes by the SLC1A4 gene. The SLC1A4 gene is mapped to chromosome 2p14 based on an alignment of the SLC1A4 sequence with the genomic sequence(GRCh37). ASCT1 does not transport glutamate or aspartate but alanine, serine, cysteine, and threonine instead. It is found that the ASCT1 transporter functions primarily as an amino acid exchanger. Transport is associated with a chloride channel activity that is thermodynamically uncoupled from animo acid transport. This gene also exhibits sodium dependence.

Synonyms: Alanine/serine/cysteine/threonine transporter 1 antibody|ASCT-1 antibody|ASCT1 antibody|AW045657 antibody|Glutamate/neutral amino acid transporter antibody|Neutral amino acid transporter A antibody|OTTHUMP00000159933 antibody|OTTHUMP00000235138 antibody|SATT antibody|SATT_HUMAN antibody|SLC1A4 antibody|Solute carrier family 1(glutamate/neutral amino acid transporter), member 4 antibody|Solute carrier family 1 member 4 antibody

UniProt: P43007

Pathways: Dicarboxylic Acid Transport