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SMURF2 antibody (Middle Region)

SMURF2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3044498
  • Target See all SMURF2 Antibodies
    SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))
    Binding Specificity
    • 16
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 317-351, Middle Region
    Reactivity
    • 66
    • 29
    • 20
    Human
    Host
    • 63
    • 3
    Rabbit
    Clonality
    • 55
    • 11
    Polyclonal
    Conjugate
    • 20
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMURF2 antibody is un-conjugated
    Application
    • 54
    • 34
    • 29
    • 18
    • 14
    • 13
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase SMURF2(SMURF2) detection. Tested with WB in Human.
    Sequence
    DHNNRTTQFT DPRLSANLHL VLNRQNQLKD QQQQQ
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase SMURF2(SMURF2) detection. Tested with WB in Human.
    Gene Name: SMAD specific E3 ubiquitin protein ligase 2
    Protein Name: E3 ubiquitin-protein ligase SMURF2
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human SMURF 2 (317-351aa DHNNRTTQFTDPRLSANLHLVLNRQNQLKDQQQQQ), identical to the related mouse sequence.
    Isotype
    IgG
    Top Product
    Discover our top product SMURF2 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))
    Alternative Name
    SMURF2 (SMURF2 Products)
    Synonyms
    SMURF2 antibody, 2810411E22Rik antibody, AI558114 antibody, AI649275 antibody, RGD1310067 antibody, wu:fb82a11 antibody, wu:fc41c02 antibody, SMAD specific E3 ubiquitin protein ligase 2 antibody, SMAD specific E3 ubiquitin protein ligase 2 S homeolog antibody, SMURF2 antibody, smurf2 antibody, Smurf2 antibody, smurf2.S antibody
    Background
    E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene. The SMURF2 gene is mapped to chromosome 17q22-q23 based on sequence similarity between the SMURF2 sequence and a genomic contig. SMURF2 is a HECT domain E3 ubiquitin ligase involved in degradation of SMADs, TGF-beta receptor (TGFBR), and other substrates. It also functions in regulation of neuronal and planar cell polarity, induction of senescence, and tumor suppression

    Synonyms: E3 ubiquitin-protein ligase SMURF2 antibody|EC 6.3.2. antibody|hSMURF2 antibody|MGC138150 antibody|Smad specific E3 ubiquitin ligase 2 antibody|SMAD specific E3 ubiquitin protein ligase 2 antibody|SMAD ubiquitination regulatory factor 2 antibody|SMAD-specific E3 ubiquitin-protein ligase 2 antibody|SMUF2_HUMAN antibody|Smurf2 antibody|Ubiquitin protein ligase SMURF2 antibody
    Gene ID
    64750
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