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CPI-17 antibody
PPP1R14A
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
4H10
unconjugated
Product Details anti-CPI-17 Antibody
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Target
See all CPI-17 (PPP1R14A) Antibodies
CPI-17 (PPP1R14A)
(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
Reactivity
All reactivities for CPI-17 antibodies
Human
Host
All hosts for CPI-17 antibodies
Mouse
Clonality
All clonalities for CPI-17 antibodies
Monoclonal
Conjugate
All conjugates for CPI-17 antibodies
This CPI-17 antibody is un-conjugated
Application
All applications for CPI-17 antibodies
Western Blotting (WB), ELISA
Purification
The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
Immunogen
Recombinant human PPP1R14A (1-147aa), Accession / GI number: NP_150281
Clone
4H10
Isotype
IgG2a kappa
Top Product
Discover our top product PPP1R14A Primary Antibody
Alternatives
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Application Details
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Application Notes
Recommended dilution 1:500
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1mg/ml
Buffer
In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Target Details for CPI-17
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Target
CPI-17 (PPP1R14A)
(Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
Alternative Name
PPP1R14A (PPP1R14A Products )
Synonyms
MGC81874 antibody, cpi-17 antibody, ppp1inl antibody, CPI-17 antibody, im:7147597 antibody, ppp1r14a antibody, zgc:110700 antibody, PPP1R14A antibody, CPI17 antibody, PPP1INL antibody, Cpi17 antibody, 1110001M11Rik antibody, protein phosphatase 1 regulatory inhibitor subunit 14A L homeolog antibody, protein phosphatase 1 regulatory inhibitor subunit 14A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14Aa antibody, protein phosphatase 1, regulatory (inhibitor) subunit 14A antibody, ppp1r14a.L antibody, ppp1r14a antibody, ppp1r14aa antibody, PPP1R14A antibody, Ppp1r14a antibody
Background
PPP1R14A (Protein phosphatase 1 regulatory subunit 14A) is a phosphorylation-dependent inhibitory protein for smooth muscle myosin phosphate. Myosin phosphatase can reverse MYL (myosin light chain) phosphorylation to induce a state of relaxation. However, during agonist-induced contraction at constant Ca2+ concurrent inhibition of myosin phosphatase leads to increases in MYL phosphorylation and tension. These calcium-independent increases in myosin phosphorylation and tension are termed calcium sensitization. Concentration: 1 mg/ml
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