Toll-Like Receptor 11 (Tlr11) (Internal Domain) antibody

Details for Product No. ABIN307011
Antigen
Epitope
Internal Domain
19
4
3
3
2
2
1
1
Reactivity
Mouse (Murine)
38
7
4
3
3
Host
Rabbit
39
2
2
Clonality
Polyclonal
Conjugate
Un-conjugated
3
1
1
1
Application
Western Blotting (WB)
38
11
8
7
5
4
4
3
1
1
Options
Isotype IgG
Antigen
Alternative Name Toll-like receptor 11 (TLR11) (IN) (Tlr11 Antibody Abstract)
Background Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).
UniProt Q6R5P0
Pathways Activation of Innate immune Response
Application Notes TLR11 antibody polyclonal antibody can be used for detection of TLR11 by Western blot at 0.5 to 2 ug/ml.. Positive Control: Positive Control RAW26.7 Cell Lysate Located in the membrane.
Restrictions For Research Use only
Concentration 0.5 mg/ml
Storage -20 °C
Supplier Images
Image no. 1 for anti-Toll-Like Receptor 11 (Tlr11) (Internal Domain) antibody (ABIN307011) Western blot analysis of TLR11 in RAW264.7 cell lysates with TLR11 antibody at (A) 0....