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5mC antibody Primary Antibody

Reactivity: Human, Mouse ChIP Host: Mouse Monoclonal
Catalog No. ABIN3071645
$1,016.28
Plus shipping costs $45.00
50 μL
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Delivery in 7 to 8 Business Days
  • Target
    Reactivity
    Human, Mouse
    Host
    Mouse
    Clonality
    Monoclonal
    Application
    Chromatin Immunoprecipitation (ChIP)
    Specificity
    Recognises the C-terminal peptide of human histone H3.
    Purification
    Protein G (affinity purified)
  • Application Notes
    Chromatrap technology: 1:4 (gDNA:antibody)
    Please note: Optimal antibody dilutions should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid multiple free/thaw cycles as this may denature the antibody
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    Background
    5mC (5---Methylcytosine) is a region of DNA that has been epigenetically modified through the addition of a methyl group at the 5th carbon position of cytosine. DNA methylation is a repressive histone modification that is associated with switching off gene expression. This methylation generally occurs at CpG islands and is also associated with genomic imprinting. Aberrant DNA methylation is linked to disease including many cancers.
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