ABCC8 antibody (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8) (C-Term)

Details for Product anti-ABCC8 Antibody No. ABIN314241
Antigen
Epitope
C-Term
26
9
4
4
2
2
1
1
1
1
1
1
Reactivity
Human
73
42
38
25
2
2
2
2
1
1
1
1
Host
Goat
40
34
7
Clonality
Polyclonal
Conjugate
This ABCC8 antibody is un-conjugated
5
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
66
43
30
29
26
5
5
2
1
1
1
1
Options
Immunogen Peptide with sequence C-EFDKPEKLLSRKD corresponding to C-Terminus according to NP_000343.2.
Purification Immunogen affinity purified
Antigen
Alternative Name SUR1 (ABCC8 Antibody Abstract)
Background Gene Symbol: ABCC8
Gene ID 6833
UniProt Q09428
Pathways Negative Regulation of Hormone Secretion
Application Notes Western Blot 0.5 - 1.5 μg/mL, Peptide ELISA Detection limit 1:8000WB: Approx. 170 kDa band observed in human brain (cerebellum) lysates (calculated MW of 177 kDa band according to NP_000343.2). An additional band of unknown identity was also consistently observed at 23 kDa. This band was successfully blocked by incubation with the immunizing peptide.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer 0.5 mg/mL Tris ( pH 7.3) and 0.5 % BSA
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8) (C-Term) antibody (ABIN314241) Western Blot: SUR1 Antibody [NBP1-00138] - (0.5ug/ml) staining of Human Cer(35ug prot...
Product cited in: de Wet, Rees, Shimomura, Aittoniemi, Patch, Flanagan, Ellard, Hattersley, Sansom, Ashcroft: "Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 48, pp. 18988-92, 2007 (PubMed).