Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibody

Details for Product No. ABIN3170507
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
107
10
7
2
2
1
1
1
Host
Rabbit
93
7
6
1
Clonality
Polyclonal
Conjugate
Un-conjugated
7
6
6
5
5
5
2
2
2
2
2
2
1
1
1
1
1
Application
Dot Blot (DB), Western Blotting (WB)
90
53
37
17
13
8
8
4
2
2
1
Options
Purpose Polyclonal antibody against KLH
Immunogen Human recombinant AKR1C3
Isotype IgG
Characteristics Polyclonal antibody against KLH
Purification Affinity purified rabbit IgG
Antigen
Alternative Name AKR1C3 (AKR1C3 Antibody Abstract)
Background Aldo-keto reductase family 1 member C3 in humans is encoded by the AKR1C3 gene. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation.
Synonyms: Aldo-keto reductase family 1, member C3, DD3, DDX, HA1753, HAKRB, HAKRe, hluPGFS, HSD17B5
Gene ID 8644
UniProt P42330
Pathways Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
Application Notes Western blot: 1-4 μg/mL, Dot blot: 1-4 μg/mL
Comment

Suggested positive control:
Western blot

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 100 μg (0.5 mg/mL) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin® and 50 % glycerol.
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use
Storage -20 °C
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibody (ABIN3170507) Western blot analysis of h AKR1C3 using anti- h AKR1C3 antibody: Lane 1: HeLa cell ly...