Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 3-32), (N-Term) antibody

Details for Product No. ABIN3170508
Antigen
Epitope
AA 3-32, N-Term
15
11
9
9
7
5
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Monkey
88
31
20
4
1
1
1
1
1
1
1
1
Host
Rabbit
86
1
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
56
41
28
18
15
13
13
4
4
4
1
Options
Purpose Polyclonal antibody against EDG4
Immunogen KLH conjugated synthetic peptide between 3-32 AA from the N-terminal region of human EDG4
Isotype IgG
Characteristics Polyclonal antibody against EDG4
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Antigen
Alternative Name EDG4 (LPAR2 Antibody Abstract)
Background EDG4 is a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. It plays a key role in phospholipase C-beta (PLC-beta) signaling pathway and stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.
Synonyms: Lysophosphatidic acid receptor 2, LPA receptor 2, LPA-2, Lysophosphatidic acid receptor Edg-4, LPAR2, EDG4, LPA2
Gene ID 9170
UniProt Q9HBW0
Application Notes WB: 1:1000, IHC: 1:50~100
Comment

Suggested positive control:
Western blot, IHC

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer 100 μg (0.5 mg/mL) of antibody in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use
Storage -20 °C
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 3-32), (N-Term) antibody (ABIN3170508) Formalin-fixed and paraffin-embedded human cancer tissue reacted with EDG4 antibody (...
Image no. 2 for anti-Lysophosphatidic Acid Receptor 2 (LPAR2) (AA 3-32), (N-Term) antibody (ABIN3170508) Western blot analysis using EDG4 (NT) antibody of cell lysates from: (A) MDA-MB-231 (...