alpha Fetoprotein antibody

Catalog No. ABIN317211

The Mouse Monoclonal anti-alpha Fetoprotein antibody (Clone 2I9-2) (ABIN317211) specifically detects alpha Fetoprotein in EIA. The antibody is reactive with Human samples.

Quick Overview for alpha Fetoprotein antibody (ABIN317211)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha Fetoprotein antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: 2I9-2

Product Details anti-alpha Fetoprotein Antibody

Specificity: This antibody recognises alpha fetoprotein (AFP), a member of the albuminoid superfamily. This antibody does not cross-react with human albumin and other human serum proteins.

Characteristics: Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP

Purification: Affinity chromatography

Immunogen: Native, from foetal cord

Isotype: IgG

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 4.4 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Expiry Date: 12 months

Target Details for alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Background: Alpha fetoprotein is a 68kD plasma protein found in fetuses over four weeks old, produced by the yolk sac and the fetal liver, with the highest concentration reached during the 12th to 16th week of gestation. It binds and transports various ligands such as bilirubin, fatty acids, steroids, heavy metals and various drugs. After birth, plasma levels drop to trace amounts in healthy adults. Elevated AFP levels are indicative of certain cancers, particularly hepatocellular carcinoma, cancer of the testes or ovaries or a malignant teratoma. During pregnancy increased levels of AFP may indicate neural tube defects such as spina bifida, while decreased levels could indicate Down's syndrome.Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP

Gene ID: 174

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process