FZD1 antibody
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- Target See all FZD1 (Fzd1) Antibodies
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FZD1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificity
- This antibody detects endogenous levels of Frizzled-1 protein.(region surrounding Leu55)
- Purification
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product Fzd1 Primary Antibody
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- Application Notes
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ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
- Alternative Name
- FZD1 / Frizzled-1 (Fzd1 Products)
- Synonyms
- CG17697 antibody, CG3646 antibody, DFZ1 antibody, DFz antibody, DFz1 antibody, Dfz1 antibody, Dm Fz1 antibody, Dmel\\CG17697 antibody, FZ antibody, Frz antibody, Fz antibody, Fz1 antibody, frz antibody, fz1 antibody, fz[[1]] antibody, Fz-1 antibody, cFz-1 antibody, Xfrizzled-1 antibody, frizzled1 antibody, frz-1 antibody, frz1 antibody, fzd1-A antibody, AW227548 antibody, FZ-1 antibody, frizzled antibody, frizzled class receptor 1 antibody, frizzled class receptor 1 L homeolog antibody, fz antibody, FZD1 antibody, Fzd1 antibody, fzd1.L antibody
- Background
- The frizzled gene, originally identified in Drosophila melanogaster, is involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several secreted mammalian frizzled-related proteins: FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3, FRP-4 and SARP3 (also designated FRP-5), have been identified. The frizzled proteins contain seven transmembrane domains, a cysteine-rich domain in the extracellular region and a carboxy terminal Ser/Thr-xxx-Val motif. They function as receptors for Wnt. The frizzled-1 gene maps to human chromosome 7q21 and is expressed in adult heart, placenta, lung, kidney, pancreas, prostate and ovary and in fetal lung and kidney. Frizzled-2 is expressed in adult heart and fetal brain, lung and kidney. The frizzled related proteins FRP-1, FRP-2, FRP-3, FRP-4 and SARP3 are secreted proteins of approximately 30 kDa that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled and a conserved hydrophilic carboxy terminal.Synonyms: Fz-1, FzE1, hFz1
- Molecular Weight
- approx. 71 kDa
- Gene ID
- 8321
- NCBI Accession
- NP_003496
- UniProt
- Q9UP38
- Pathways
- WNT Signaling, Asymmetric Protein Localization
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