KAT2A antibody

Catalog No. ABIN317677

Product Details anti-KAT2A Antibody

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of GCN5 protein.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Alternative Name: KAT2A / GCN5L2 (KAT2A Products)

Synonyms: KAT2A antibody, GCN5L2 antibody, GCN5 antibody, PCAF-b antibody, hGCN5 antibody, 1110051E14Rik antibody, AW212720 antibody, Gcn5 antibody, Gcn5l2 antibody, mmGCN5 antibody, K(lysine) acetyltransferase 2A antibody, lysine acetyltransferase 2A antibody, histone acetyltransferase KAT2A antibody, ras-related protein Rab-5C antibody, KAT2A antibody, LOC100176452 antibody, LOC100597293 antibody, Kat2a antibody

Background: KAT2A / GCN5 is a transcriptional co-activator that has histone acetyltransferase activity. It exhibits significant histone acetyltransferase activity with core histones but not with nucleosome core particles. KAT2A is a component of the TFTC-HAT and STAGA complexes. KAT2A is also recruited by the viral protein Tat during HIV infection, inducing chromatin remodelling of proviral genes.Synonyms: General control of amino acid synthesis protein 5-like 2, HGCN5, Histone acetyltransferase GCN5, Histone acetyltransferase KAT2A, HsGCN5, Lysine acetyltransferase 2A, STAF97

Molecular Weight: approx. 100 kDa

Gene ID: 2648

NCBI Accession: NP_066564

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation