ELOVL1 antibody

Catalog No. ABIN317834

Product Details anti-ELOVL1 Antibody

Target: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELOVL1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: ELOVL1 antibody detects endogenous levels of ELOVL1 protein.(region surrounding Phe139)

Purification: Affinity Chromatography using epitope-specific immunogen

Application Details

Application Notes: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ELOVL1

Target: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Alternative Name: ELOVL1 (ELOVL1 Products)

Synonyms: AA407424 antibody, BB151133 antibody, Ssc1 antibody, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 antibody, ELOVL fatty acid elongase 1 antibody, Elovl1 antibody, ELOVL1 antibody

Background: Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.Synonyms: 3-keto acyl-CoA synthase ELOVL1, CGI-88, Elongation of very long chain fatty acids protein 1, SSC1

Molecular Weight: approx. 35 kDa

Gene ID: 64834

NCBI Accession: NP_073732

UniProt: Q9BW60