Glucagon antibody (AA 19-29)

Catalog No. ABIN318560

Product Details anti-Glucagon Antibody

Target: Glucagon (GCG)

Binding Specificity: AA 19-29

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This Glucagon antibody is un-conjugated

Application: Radioimmunoassay (RIA)

Specificity: This antibody is specific for the C terminal of Glucagon, a linear peptide of 29 amino acids. Its primary sequence is highly conserved among vertebrates.

Purification: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Glucagon amino acids 19-29, prepared by enzymatic cleavage of Porcine glucagon, conjugated with bovine thyroglobulin carrier protein.

Isotype: IgG

Application Details

Application Notes: Radioimmunoassays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3) 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Glucagon

Target: Glucagon (GCG)

Alternative Name: Glucagon (GCG Products)

Synonyms: GLP1 antibody, GLP2 antibody, GRPP antibody, GLP-1 antibody, Glu antibody, PPG antibody, GCG antibody, gcg-A antibody, gcg1 antibody, glucagon antibody, glucagon L homeolog antibody, GCG antibody, Gcg antibody, gcg.L antibody

Background: Glucagon is a hormone that is secreted by alpha cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.Synonyms: GCG

Gene ID: 2641

NCBI Accession: NP_002045

UniProt: P01275

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling