GABRB1 antibody (Ser434)

Catalog No. ABIN319328

Product Details anti-GABRB1 Antibody

Target: GABRB1 (gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))

Binding Specificity: Ser434

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRB1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of total GABRB1 protein.

Purification: Immunoaffinity Chromatography.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human GABRB1 around the phosphorylation site of Serine 434 (R-A-SP-Q-L).

Application Details

Application Notes: Western Blot (1/500-1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at-20 °C.

Target Details for GABRB1

Target: GABRB1 (gamma-aminobutyric Acid (GABA) A Receptor, Subunit beta 1 (GABRB1))

Alternative Name: GABRB1 (GABRB1 Products)

Synonyms: AW061132 antibody, B230208N19Rik antibody, Gabrb-1 antibody, GARB1 antibody, si:dkey-20i10.4 antibody, gamma-aminobutyric acid type A receptor beta1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 antibody, gamma-aminobutyric acid type A receptor beta 1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, beta 1 antibody, GABRB1 antibody, Gabrb1 antibody, gabrb1 antibody

Background: GABA A Receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA A Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.Synonyms: GABA A receptor subunit beta-1, GABRB-1, Gamma-aminobutyric acid receptor subunit beta-1

Gene ID: 2560

NCBI Accession: NP_000803

UniProt: P18505