KEL antibody (Kell Blood Group, Metallo-Endopeptidase)

Details for Product anti-KEL Antibody No. ABIN319444, Supplier: Log in to see
Antigen
  • CD238
  • Ece3
  • ECE3
  • Kell blood group
  • Kell blood group, metallo-endopeptidase
  • Kel
  • KEL
Reactivity
Human
48
5
2
Host
Mouse
39
8
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This KEL antibody is un-conjugated
3
3
3
2
2
2
Application
Immunoprecipitation (IP)
37
26
20
4
4
3
3
2
2
1
1
Options
Supplier
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Immunogen Human erythrocytes
Clone BRIC203
Isotype IgG1
Specificity This antibody recognises CD238, also known as the kell blood group antigen Kpbc. The kell blood group antigens are carried on a 93 kDa erythrocyte membrane glycoprotein. In haemaggulation tests, MCA1987T reacts with Kp (a-b+) but not Kp (a+b-). In addition this antibody will agglutinate Kp (a+b-c+) and Kp (a-b-c+) erythrocytes but not react with Ko erythrocytes.
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Plasmids, Primers & others Plasmids, Primers & others KEL products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD238 / KEL (KEL Antibody Abstract)
Background Blood Group Kell Antigen is a type II transmembrane glycoprotein. The Kell glycoprotein links to the XK membrane protein, that carries the Kx antigen via a single disulfide bond. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.Synonyms: Kell blood group glycoprotein
Gene ID 3792
NCBI Accession NP_000411
UniProt P23276
Application Notes Immunoprecipitation. Haemagglutination.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0mg/mL
Buffer Tris buffered glycine, pH 7.8 containing 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Parsons, Gardner, Anstee: "Monoclonal antibodies against Kell glycoprotein: serology, immunochemistry and quantification of antigen sites." in: Transfusion medicine (Oxford, England), Vol. 3, Issue 2, pp. 137-42, 1993 (PubMed).