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TPSAB1 antibody

TPSAB1 Reactivity: Human, Rat, Dog, Cat, Monkey WB, IHC (p), IHC (fro), EIA Host: Mouse Monoclonal AA1 unconjugated
Catalog No. ABIN319873
  • Target See all TPSAB1 Antibodies
    TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
    Reactivity
    • 47
    • 34
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    Human, Rat, Dog, Cat, Monkey
    Host
    • 67
    • 19
    • 2
    • 1
    Mouse
    Clonality
    • 72
    • 17
    Monoclonal
    Conjugate
    • 46
    • 17
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TPSAB1 antibody is un-conjugated
    Application
    • 71
    • 40
    • 27
    • 12
    • 11
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Specificity
    This antiobdy recognises Mast Cell Tryptase, both alpha and beta isoforms. This antibody is an excellent marker for mast cells, and does not bind to any other cell type in immunohistology.
    Purification
    Affinity Chromatography on Protein G
    Immunogen
    Human mast cell tryptase purified from Human lung tissue. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
    Clone
    AA1
    Isotype
    IgG1
    Top Product
    Discover our top product TPSAB1 Primary Antibody
  • Application Notes
    ELISA. Western Blot. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections (1/10,000): This product requires either protein digestion pre-treatment of paraffin sections e.g. pronase, or HIER, Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Tonsil.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
    Alternative Name
    Tryptase beta-1 (TPSAB1) (TPSAB1 Products)
    Synonyms
    TPS1 antibody, TPS2 antibody, TPSB1 antibody, PMCT7 antibody, tpsab1 antibody, tryptaseB antibody, tryptaseC antibody, MMCP-7 antibody, Mcp-7 antibody, Mcp7 antibody, Mcpt7 antibody, rMCP-7 antibody, AV011504 antibody, MMCP-6 antibody, Mcp-6 antibody, Mcp6 antibody, Mcpt6 antibody, tryptase alpha/beta 1 antibody, tryptase antibody, tryptase beta 2 (gene/pseudogene) antibody, tryptase beta 2 antibody, TPSAB1 antibody, MCT7 antibody, tpsab1 antibody, TPSB2 antibody, Tpsab1 antibody, Tpsb2 antibody
    Background
    Mast cells contain a number of preformed chemical mediators such as histamine, chymase, carboxypeptidase and proteolytic tryptase. Human Mast Cell Tryptase is considered to be an important marker of mast cell activation as well as an important mediator of inflammation.Synonyms: Mast Cell Tryptase, TPSB1, Tryptase I
    Gene ID
    100507804
    NCBI Accession
    NP_003285
    UniProt
    Q15661
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