ITPR1 antibody (AA 1892-1911)
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- Target See all ITPR1 Antibodies
- ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
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Binding Specificity
- AA 1892-1911
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Reactivity
- Human, Mouse, Rat, Cow, Monkey
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ITPR1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Brand
- IHC-plus™
- Specificity
- Recognizes human IP3R-I. Detects a band of ~240kD by Western Blot. Species cross-reactivity: mouse, rat and canine.
- Predicted Reactivity
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine (100%) Hamster, Elephant, Panda, Horse (95%) Opossum (85%).
- Purification
- Affinity purified
- Immunogen
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Synthetic peptide corresponding to aa 1892-1911 (N1892KKKDDEVDRDAPSRKKAKE1911) of the cytoplasmic C-terminal domain of human IP3R-I (inositol 1,4,5-triphosphate receptor (type-I)). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine (100%), Hamster, Elephant, Panda, Horse (95%), Opossum (85%).
Type of Immunogen: Synthetic peptide - Isotype
- IgG
- Top Product
- Discover our top product ITPR1 Primary Antibody
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- Application Notes
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Approved: ICC, IHC, IHC-Fr (1:125), IHC-P (5 μg/mL), IP, WB (1:500)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 1 mg/mL BSA, 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
- Alternative Name
- ITPR1 / IP3 Receptor Type 1 (ITPR1 Products)
- Synonyms
- D6Pas2 antibody, ENSMUSG00000072853 antibody, Gm10429 antibody, IP3R1 antibody, InsP3R antibody, Ip3r antibody, Itpr-1 antibody, P400 antibody, Pcp-1 antibody, Pcp1 antibody, opt antibody, I145TR antibody, InsP3R1 antibody, INSP3R1 antibody, IP3R antibody, SCA15 antibody, SCA16 antibody, SCA29 antibody, inositol 1,4,5-trisphosphate receptor type 1 antibody, inositol 1,4,5-trisphosphate receptor 1 antibody, inositol 1,4,5-trisphosphate receptor, type 1 antibody, ITPR1 antibody, Itpr1 antibody
- Background
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Name/Gene ID: ITPR1
Subfamily: Inositol 1,4,5-triphosphate receptor
Family: Ion Channel
Synonyms: ITPR1, InsP3R-I, IP3R1, InsP3R, InsP3R type I, INSP3R1, IP3R, Opisthotonus, Pcp1, IP3 receptor, IP3 receptor isoform 1, SCA15, Spinocerebellar ataxia 15, Spinocerebellar ataxia 16, I145TR, IP3R 1, KIAA1754, SCA16, Type 1 InsP3 receptor - Gene ID
- 3708
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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