XRCC6 antibody

Catalog No. ABIN342410

Product Details anti-XRCC6 Antibody

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This XRCC6 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Recognizes the small ~ subunit (~70 kD)of placental PSE1 and human Ku in solution and when bound to DNA.

Purification: Protein G purified

Immunogen: Proximal sequence element (PSE1) of the human U1 small nuclear RNA extracted from human placenta.

Type of Immunogen: Synthetic peptide

Clone: N3H10

Isotype: IgG2b

Application Details

Application Notes: Approved: WB

Usage: Works well in Western blot and electrophoretic mobility (gel shift) assays for identifying PSE1 or Ku. May be used to immuno-deplete Ku protein from protein mixtures prior to specific DNA affinity chromatography.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for XRCC6

Target: XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Alternative Name: XRCC6 / Ku70 (XRCC6 Products)

Synonyms: CTC75 antibody, CTCBF antibody, G22P1 antibody, KU70 antibody, ML8 antibody, TLAA antibody, 70kDa antibody, G22p1 antibody, Ku70 antibody, Kup70 antibody, X-ray repair cross complementing 6 antibody, ATP-dependent DNA helicase II, 70 kDa subunit antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog antibody, X-ray repair complementing defective repair in Chinese hamster cells 6 antibody, XRCC6 antibody, Bm1_41430 antibody, xrcc6.L antibody, Xrcc6 antibody

Background: Name/Gene ID: XRCC6

Synonyms: XRCC6, 5-dRP lyase Ku70, 70 kDa subunit of Ku antigen, CTCBF, DNA repair protein XRCC6, D22S671, D22S731, G22P1, Ku autoantigen, 70  kDa, Ku autoantigen p70 subunit, Thyroid-lupus autoantigen p70, TLAA, CTC75, KU70, ML8, Thyroid-lupus autoantigen

Gene ID: 2547

UniProt: P12956

Pathways: DNA Damage Repair